• Publications
  • Influence
Effect of temperature, pH and electron donor on the microbial reductive dechlorination of chloroalkenes
In order to elucidate the effect of environmental conditions such as pH, temperature, and electron donor on the microbial reductive dechlorination of tetrachloroethylene and its transformationExpand
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Amino acid and fatty acid compositions and nutritional quality of muscle in the pomfret, Pampus punctatissimus
Abstract The pomfret, Pampus punctatissimus , is an important fisheries resource in China, but little is known about its amino acid and fatty acid compositions. Pomfret muscle contained 18.6% crudeExpand
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Mechanistic Studies of R67 Dihydrofolate Reductase
R67 dihydrofolate reductase (DHFR) is encoded by an R-plasmid, and expression of this enzyme in bacteria confers resistance to the antibacterial drug, trimethoprim. This DHFR variant is notExpand
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Orientation of Heparin-binding Sites in Native Vitronectin
A primary heparin-binding site in vitronectin has been localized to a cluster of cationic residues near the C terminus of the protein. More recently, secondary binding sites have been proposed. InExpand
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  • Open Access
Artificial duplication of the R67 dihydrofolate reductase gene to create protein asymmetry. Effects on protein activity and folding.
R67 dihydrofolate reductase (DHFR), encoded by an R plasmid, provides resistance to the antibacterial drug trimethoprim. This enzyme does not exhibit any structural or sequence homologies withExpand
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Native and Multimeric Vitronectin Exhibit Similar Affinity for Heparin
For many years, the concept that the heparin-binding sequence is sequestered within vitronectin and exposed upon denaturation of the protein has guided experimental design and interpretation ofExpand
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Reductive dechlorination of chloroalkenes in microcosms developed with a field contaminated soil
Abstract Static microcosms were constructed with a low organic carbon content, field-contaminated soil containing (in μmol/kg wet soil) tetrachloroethylene (PCE; 69.1), trichloroethylene (TCE; 18.1)Expand
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Characterization of the Denaturation and Renaturation of Human Plasma Vitronectin
Upon treatment with denaturing agents, vitronectin has been observed to exhibit conformational alterations which are similar to the structural changes detected when vitronectin binds theExpand
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Characterization of the Denaturation and Renaturation of Human Plasma Vitronectin
Unfolding and refolding of plasma vitronectin appear irreversible under near physiological conditions, with rearrangements of disulfides and self-association to a multimeric form observed asExpand
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  • Open Access
Equilibrium folding studies of tetrameric R67 dihydrofolate reductase.
R67 dihydrofolate reductase (DHFR) is an R-plasmid encoded enzyme that confers resistance to the antibacterial drug trimethoprim. This enzyme is not homologous in sequence or structure to chromosomalExpand
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