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Gentamicin-loaded hydraulic calcium phosphate bone cement as antibiotic delivery system.
- M. Bohner, J. Lemaître, P. Van Landuyt, P. Zambelli, H. Merkle, B. Gander
- Materials ScienceJournal of pharmaceutical sciences
- 1 May 1997
A hydraulic calcium phosphate cement made of beta-tricalcium phosphate, monocalcium phosphate monohydrate, and water was used as a delivery system for the antibiotic gentamicin sulfate (GS), indicating that no irreversible binding occurred between the cement paste and the antibiotic.
Local delivery of bisphosphonate from coated orthopedic implants increases implants mechanical stability in osteoporotic rats.
- B. Peter, O. Gauthier, D. Pioletti
- Biology, MedicineJournal of biomedical materials research. Part A
It is shown that orthopedic implants containing bisphosphonates could be beneficial for osteoporotic patients in need of a total joint replacement.
Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration.
Bone tissue engineering using foetal cell therapy.
- D. Pioletti, M. Montjovent, P. Zambelli, L. Applegate
- Biology, MedicineSwiss medical weekly
- 9 September 2006
Different cell sources for bone tissue engineering are reviewed, foetal bone cells are presented as an alternative solution, and potentially interesting therapeutic options are proposed.
Computer-assisted placement technique in hip resurfacing arthroplasty: improvement in accuracy?
Hip navigation for resurfacing surgery may allow improved visualisation and hip implant positioning, but its advantage probably will be more obvious with mini-incisions than with regular incision surgery.
Immediate hip spica is as effective as, but more efficient than, flexible intramedullary nailing for femoral shaft fractures in pre-school children
- Nicolas Jauquier, Martina Doerfler, F. Haecker, C. Hasler, P. Zambelli, N. Lutz
- MedicineJournal of children's orthopaedics
- 5 August 2010
In a pre-school child with a femoral shaft fracture, immediate SCI applied by a paediatric orthopaedic team following specific guidelines allowed early discharge from hospital with few complications.
Fetal bone cells for tissue engineering.
How plate positioning impacts the biomechanics of the open wedge tibial osteotomy; A finite element analysis
- L. Blecha, P. Zambelli, N. Ramaniraka, P. Bourban, J. Manson, D. Pioletti
- Engineering, MedicineComputer methods in biomechanics and biomedical…
- 1 October 2005
A numerical model of the medial open wedge tibial osteotomy based on the finite element method was developed and found that to avoid formation of fibrous tissue at the bone wedge interface, the osteotomy should be loaded under 18.8% of the normal gait load until the osteotom interfaces union is achieved.
NBAS mutations cause a multisystem disorder involving bone, connective tissue, liver, immune system, and retina
- N. G. Segarra, D. Ballhausen, L. Bonafė
- Medicine, BiologyAmerican journal of medical genetics. Part A
- 1 December 2015
Observations indicate that the phenotypic spectrum of NBAS deficiency is wider than previously known and includes skeletal, hepatic, metabolic, and immunologic aspects.
Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives.
- A. Bregou Bourgeois, B. Aubry-Rozier, L. Bonafė, L. Laurent-Applegate, D. Pioletti, P. Zambelli
- Medicine, BiologySwiss medical weekly
- 20 June 2016
Multidisciplinary management improves quality of life for patients with osteogenesis imperfecta and innovative therapies, such as progenitor and mesenchymal stem cell transplantation, targeting the specific altered pathway rather than the symptoms, are in the process of development.