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Multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypox
TLDR
Using independent and internally validated diagnostic approaches with ≥95% sensitivity and ≥90% specificity for detecting clinical monkeypox infection, three previously unreported cases of monkeypox in preimmune individuals are identified at 13, 29 and 48 years after smallpox vaccination, showing that cross-protective antiviral immunity against West African monkeypox can potentially be maintained for decades after small vaccination.
Clinical evaluation of oral fluid samples for diagnosis of viral hepatitis
TLDR
It is proposed that oral sampling represents a safer and more convenient procedure for reliable hepatitis virus testing than blood sampling and that it has wide application in patient and outbreak management.
Monoclonal Antibody Detection of CD46 Clustering beneath Neisseria gonorrhoeae Microcolonies
TLDR
The construction of Cyt1- and Cyt2-specific monoclonal antibodies (MAbs) that recognize unique epitopes within the tails and can be used for immunofluorescence microscopy, immunoblotting, and immunoprecipitation are reported.
Active Specific Immunotherapy with a β-Human Chorionic Gonadotropin Peptide Vaccine in Patients with Metastatic Colorectal Cancer: Antibody Response Is Associated with Improved Survival
TLDR
Vaccination with CTP37-DT induced anti-hCG antibody induction was associated with longer overall survival and has an excellent safety profile and warrants further study in patients with colorectal cancer.
Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival.
TLDR
Vaccination with CTP37-DT induced anti-hCG antibody induction was associated with longer overall survival and has an excellent safety profile and warrants further study in patients with colorectal cancer.
Antibody-mediated protection against respiratory viral infection.
TLDR
Understanding of the mechanisms underlying antibody-mediated protection against respiratory virus infections may lead to improved immunization strategies as well as more effective antibody-based therapeutics.
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