• Publications
  • Influence
Clinical and psychosocial predictors of suicide attempts and nonsuicidal self-injury in the Adolescent Depression Antidepressants and Psychotherapy Trial (ADAPT).
OBJECTIVE The authors assessed whether clinical and psychosocial factors in depressed adolescents at baseline predict suicide attempts and nonsuicidal self-injury over 28 weeks of follow-up. METHODExpand
  • 387
  • 22
Attention difficulties and mood-related ruminative response style in adolescents with unipolar depression.
BACKGROUND Depressed adults may show impairment in switching attention from one task to another. Rumination on negative thoughts is associated with the onset and persistence of depressive episodes.Expand
  • 66
  • 10
Childhood adversity and allostatic overload of the hypothalamic-pituitary-adrenal axis: a vulnerability model for depressive disorders.
Childhood adversity is associated with increased risk for onset of depressive episodes. This review will present evidence that allostatic overload of the hypothalamic-pituitary-adrenal axis (HPAA)Expand
  • 69
  • 5
  • PDF
Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms
Significance Clinical depression is a severe and common illness, characterized primarily by persistent low mood and lack of pleasure in usually enjoyable activities, that results in significantExpand
  • 90
  • 3
  • PDF
Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre,
Summary Background Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65–70% of patients. We aimed to assessExpand
  • 96
  • 3
  • PDF
Profiles of family-focused adverse experiences through childhood and early adolescence: The ROOTS project a community investigation of adolescent mental health
BackgroundAdverse family experiences in early life are associated with subsequent psychopathology. This study adds to the growing body of work exploring the nature and associations between adverseExpand
  • 81
  • 2
A Systematic Review of Amenable Resilience Factors That Moderate and/or Mediate the Relationship Between Childhood Adversity and Mental Health in Young People
Background: Up to half of Western children and adolescents experience at least one type of childhood adversity. Individuals with a history of childhood adversity have an increased risk ofExpand
  • 48
  • 2
  • PDF
Treated depression in adolescents: predictors of outcome at 28 weeks.
BACKGROUND There is great heterogeneity of clinical presentation and outcome in paediatric depression. AIMS To identify which clinical and environmental risk factors at baseline and duringExpand
  • 40
  • 2
  • PDF
5-HTTLPR and Early Childhood Adversities Moderate Cognitive and Emotional Processing in Adolescence
Background Polymorphisms in the promoter region of the serotonin transporter gene (5-HTTLPR) and exposure to early childhood adversities (CA) are independently associated with individual differencesExpand
  • 40
  • 2
  • PDF
Cognitive-behavioural therapy and short-term psychoanalytic psychotherapy versus brief psychosocial intervention in adolescents with unipolar major depression (IMPACT): a multicentre, pragmatic,
BACKGROUND Although there are effective psychological treatments for unipolar major depression in adolescents, whether or not one or more of the available therapies maintain reduced depressiveExpand
  • 24
  • 2
  • PDF