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The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress
Background: The clinical assessment and investigation of irritable bowel syndrome would be greatly facilitated by the introduction of a simple, easy to use severity scoring system. Such a system,Expand
Guidelines on the irritable bowel syndrome: mechanisms and practical management
TLDR
Better ways of identifying which patients will respond to specific treatments are urgently needed for the assessment and management of adult patients with irritable bowel syndrome. Expand
Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35624 in Women with Irritable Bowel Syndrome
TLDR
B. infantis 35624 at a dose of 1 × 108 cfu was significantly superior to placebo and all other bifidobacterium doses for the primary efficacy variable of abdominal pain as well as the composite score and scores for bloating, bowel dysfunction, incomplete evacuation, straining, and the passage of gas at the end of the 4-wk study. Expand
Intestinal microbiota in functional bowel disorders: a Rome foundation report
TLDR
A critical review of current hypotheses regarding the pathogenetic involvement of microbiota in FGID is provided and the results of microbiota-directed interventions are evaluated and clinical guidance on modulation of gut microbiota in IBS is provided. Expand
Design of treatment trials for functional gastrointestinal disorders
Until recently many clinical trials of functional gastrointestinal disorders (FGIDs) suffered from important weaknesses in trial design, study execution, and data analysis. This makes it difficult toExpand
Design of treatment trials for functional gastrointestinal disorders.
Until recently many clinical trials of functional gastrointestinal disorders (FGIDs) suffered from important weaknesses in trial design, study execution, and data analysis. This makes it difficult toExpand
CONTROLLED TRIAL OF HYPNOTHERAPY IN THE TREATMENT OF SEVERE REFRACTORY IRRITABLE-BOWEL SYNDROME
TLDR
Thirty patients with severe refractory irritable-bowel syndrome were randomly allocated to treatment with either hypnotherapy or psychotherapy and placebo, and the difference between the two groups being highly significant. Expand
Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial
TLDR
Food elimination based on IgG antibodies may be effective in reducing IBS symptoms and is worthy of further biomedical research. Expand
Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome
TLDR
The data suggest that postprandial symptomatology may be associated with increased platelet depleted plasma 5-HT concentrations in female subjects with d-IBS, and the presence of increased Platelet stores of 5- HT may act as a useful marker for the diagnosis and management of d- IBS. Expand
Non-colonic features of irritable bowel syndrome.
TLDR
A wide variety of non-gastrointestinal symptoms were significantly more common than in a group of 100 age, sex, and social class matched controls and may be indicative of a much more diffuse disorder of smooth muscle than has previously been appreciated. Expand
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