• Publications
  • Influence
Integrons and Gene Cassettes in theEnterobacteriaceae
TLDR
PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the aminoglycosides and trimethoprim. Expand
Norovirus recombination.
TLDR
NoV recombinants and their recombination breakpoints were identified using three methods: phylogenetic analysis, SimPlot analysis and the maximum chi2 method, and a total of 20 NoV recombinant types were identified in circulation worldwide. Expand
Norovirus illness is a global problem: emergence and spread of norovirus GII.4 variants, 2001-2007.
TLDR
Establishing a global NoV network by which data on strains with the potential to cause pandemics can be rapidly exchanged may lead to improved prevention and intervention strategies, and show notable differences in geographic prevalence. Expand
Emergence of a New Norovirus Genotype II.4 Variant Associated with Global Outbreaks of Gastroenteritis
TLDR
A nested reverse transcriptase PCR (nRT-PCR) that was designed to amplify the highly conserved 3′ end of the polymerase region and the 5′End of the capsid gene of NoV genogroup II (GII) was validated with strains isolated from sporadic and outbreak cases between 1997 and 2004 in Australia. Expand
Proposal for a unified norovirus nomenclature and genotyping
TLDR
It is demonstrated that the pairwise distance cutoff method can no longer be used and a phylogenetic approach to classify noroviruses is outlined and a dual nomenclature using both ORF1 and VP1 sequences is proposed, as recombination is common and recognizing recombinant viruses may be relevant. Expand
Bacterially induced bone destruction: mechanisms and misconceptions
TLDR
Much greater attention should be focused on the problem of bacterially induced bone remodelling in order to define pathogenetic mechanisms which could be therapeutic targets for the development of new treatment modalities. Expand
Evolution of AbaR-type genomic resistance islands in multiply antibiotic-resistant Acinetobacter baumannii.
TLDR
Multiply antibiotic-resistant A. baumannii strains belonging to both European epidemic clonal lineages I and II are found in Australian hospitals, indicating that these clones are globally distributed. Expand
Evidence of a large, international network of HCV transmission in HIV-positive men who have sex with men.
TLDR
An international phylogenetic study revealed a large international network of HCV transmission among HIV-positive MSM, supported by the large proportion of European MSM infected with an HCV strain co-circulating in multiple European countries, the low evolutionary distances among HCV isolates from different countries, and the trend toward increased country mixing with increasing cluster size. Expand
Rapid Evolution of Pandemic Noroviruses of the GII.4 Lineage
TLDR
The hypothesis that the ability of the virus to generate genetic diversity is vital for viral fitness is supported, as it is shown that GII.4 viruses have both a higher frequency in the host population and greater epidemiological fitness. Expand
Norovirus Recombination in ORF1/ORF2 Overlap
TLDR
Evidence is provided to support the theory of the role of subgenomic RNA promoters as recombination hotspots and a simple mechanism of how recombination might occur in NoV is described. Expand
...
1
2
3
4
5
...