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HMGB1 contributes to kidney ischemia reperfusion injury.
- H. Wu, J. Ma, +4 authors S. Chadban
- Journal of the American Society of Nephrology…
- 1 November 2010
High-mobility group box 1 (HMGB1), a nuclear factor released extracellularly as an inflammatory cytokine, is an endogenous ligand for Toll-like receptor 4 (TLR4). TLR4 activation mediates kidney… Expand
The Effect of Dietary Protein Restriction on the Progression of Diabetic and Nondiabetic Renal Diseases
End-stage renal disease is a major cause of death and disability in the United States. Many clinical studies have focused on interventions, including dietary protein restriction in both diabetic and… Expand
Effect of ginsenoside Rg1 on proliferation and differentiation of human dental pulp cells in vitro.
BACKGROUND Human dental pulp cells (hDPCs) have the potency to proliferate and differentiate into odontoblasts and play an important role in dentine formation and reparation. The aim of the present… Expand
Overexpression of 5-Lipoxygenase and Cyclooxygenase 2 in Hamster and Human Oral Cancer and Chemopreventive Effects of Zileuton and Celecoxib
Purpose: Previous studies have suggested an important role of aberrant arachidonic acid metabolism, especially the cyclooxygenase (Cox) pathway, in oral carcinogenesis. However, it is unknown whether… Expand
Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients
BackgroundThe EGFR and HER2 genes are located on chromosomes 7 and 17, respectively. They are therapeutic targets in some tumors. The TOP2A gene, which is located near HER2 on chromosome 17, is the… Expand
Upregulation of phosphodiesterase-4 in the lung of allergic rats.
- Hui-Fang Tang, Y. Song, J. Chen, J. Chen, P. Wang
- American journal of respiratory and critical care…
- 15 April 2005
Inhibitors of phosphodiesterase-4 (PDE4) are efficacious for allergic asthma in animal models and have shown some efficacy in human asthma. Regulation of PDE4 in allergy and asthma has been widely… Expand
Characterisation of dendritic cell subsets in chronically inflamed human epididymis
Infection and inflammation of the genital tract are thought to be a primary aetiological factor of male infertility. Chronic epididymitis appears to be more important than prostatitis or seminal… Expand
Malignant transformation of ovarian mature cystic teratoma into squamous cell carcinoma: a Taiwanese Gynecologic Oncology Group (TGOG) study
- A. J. Chiang, M. Y. Chen, +7 authors Chih Long Chang
- Journal of gynecologic oncology
- 17 March 2017
Objective The malignant transformation (MT) of ovarian mature cystic teratoma (MCT) to squamous cell carcinoma (SCC) is very rare. This study analyzed cases from multiple medical centers in Taiwan to… Expand
LncRNA, TUG1 regulates the oral squamous cell carcinoma progression possibly via interacting with Wnt/β-catenin signaling.
Oral squamous cell carcinoma (OSCC) is one the most common cancer affecting the head and neck region, and the molecular mechanisms underlying OSCC development is largely unknown. Long non-coding RNAs… Expand
Androgens and ovarian cancers.
Ovarian cancer is one of the most lethal malignancies in women. Numerous studies indicate that the steroid hormones have been implicated in the etiology and/or progression of epithelial ovarian… Expand