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- Publications
- Influence
Gene-centric metagenomics of the fiber-adherent bovine rumen microbiome reveals forage specific glycoside hydrolases
- Jennifer M. Brulc, Dionysios A. Antonopoulos, +11 authors B. White
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 10 February 2009
The complex microbiome of the rumen functions as an effective system for the conversion of plant cell wall biomass to microbial protein, short chain fatty acids, and gases. As such, it provides a… Expand
Nomenclatural validation of the genetically revised cyanobacterial genus Dolichospermum (RALFS ex BORNET et FLAHAULT) comb. nova.
- P. Wacklin, L. Hoffmann, J. Komárek
- Biology
- 2009
The traditional cyanobacterial genus Anabaena is heterogeneous, as follows from the modern molecular evaluation. The cluster of planktic Anabaena-morphotypes with gas vesicles in cells must be… Expand
A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial
- A. Pärtty, M. Kalliomäki, P. Wacklin, S. Salminen, E. Isolauri
- Medicine
- Pediatric Research
- 11 March 2015
Background:Recent experimental evidence suggests that gut microbiota may alter function within the nervous system providing new insight on the mechanism of neuropsychiatric… Expand
Secretor Genotype (FUT2 gene) Is Strongly Associated with the Composition of Bifidobacteria in the Human Intestine
- P. Wacklin, H. Mäkivuokko, +6 authors J. Maettoe
- Biology, Medicine
- PloS one
- 19 May 2011
Intestinal microbiota plays an important role in human health, and its composition is determined by several factors, such as diet and host genotype. However, thus far it has remained unknown which… Expand
Faecal Microbiota Composition in Adults Is Associated with the FUT2 Gene Determining the Secretor Status
- P. Wacklin, J. Tuimala, +8 authors J. Maettoe
- Biology, Medicine
- PloS one
- 14 April 2014
The human intestine is colonised with highly diverse and individually defined microbiota, which likely has an impact on the host well-being. Drivers of the individual variation in the microbiota… Expand
The Duodenal Microbiota Composition of Adult Celiac Disease Patients Is Associated with the Clinical Manifestation of the Disease
- P. Wacklin, K. Kaukinen, +5 authors J. Maettoe
- Medicine
- Inflammatory bowel diseases
- 1 April 2013
Background:Celiac disease is classically manifested in the gastrointestinal (GI) tract but extraintestinal symptoms, such as dermatitis herpetiformis (DH), are also common. Besides several well-known… Expand
Altered Duodenal Microbiota Composition in Celiac Disease Patients Suffering From Persistent Symptoms on a Long-Term Gluten-Free Diet
- P. Wacklin, Pilvi Laurikka, +8 authors K. Kaukinen
- Medicine
- The American Journal of Gastroenterology
- 1 December 2014
Objectives:A significant fraction of celiac disease patients suffer from persistent symptoms despite a long-term gluten-free diet (GFD) and normalized small bowel mucosa. The commonly suggested… Expand
Association between the ABO blood group and the human intestinal microbiota composition
- H. Mäkivuokko, S. Lahtinen, +7 authors J. Maettoe
- Biology, Medicine
- BMC Microbiology
- 6 June 2012
BackgroundThe mucus layer covering the human intestinal epithelium forms a dynamic surface for host-microbial interactions. In addition to the environmental factors affecting the intestinal… Expand
Secretor Status Is Strongly Associated with Microbial Alterations Observed during Pregnancy
- H. Kumar, P. Wacklin, +6 authors S. Salminen
- Biology, Medicine
- PloS one
- 31 July 2015
During pregnancy there are significant changes in gut microbiota composition and activity. The impact of secretor status as determined by genotyping FUT2 (fucosyltransferase 2) gene was taken as one… Expand
Association study of FUT2 (rs601338) with celiac disease and inflammatory bowel disease in the Finnish population.
- A. Parmar, N. Alakulppi, +15 authors E. Einarsdottir
- Biology, Medicine
- Tissue antigens
- 1 December 2012
Homozygosity for a nonsense mutation in the fucosyltransferase 2 (FUT2) gene (rs601338G>A) leads to the absence of ABH blood groups (FUT2 non-secretor status) in body fluids. As the secretor status… Expand