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Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds.
TLDR
Flavone, quercetin and naringenin were effective in inhibiting the growth of the organisms and purple loosestrife was the most active plant extracts against gram-positive Staphylococcus aureus. Expand
Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only
TLDR
The effects and mechanisms of naturally occurring phenolic compounds on iNOS expression and NO production in activated macrophages partially explain the pharmacological efficacy of flavonoids as anti-inflammatory compounds. Expand
Ethnobotanical and antimicrobial investigation on some species of Terminalia and Combretum (Combretaceae) growing in Tanzania.
TLDR
The results of the antimicrobial screening support the ethnomedical uses of these plants, which have medical applications against various bacterial infections, and against symptoms like diarrhoea, hypertension and even cancer. Expand
In vitro assay for human toxicity of cereulide, the emetic mitochondrial toxin produced by food poisoning Bacillus cereus.
TLDR
Exposure of four human cell lines to cereulide showed that the threshold concentration for the loss of mitochondrial membrane potential in human cells was similar to that observed in boar sperm, and boar sperms were 100 times more sensitive to Cereulide than bull sperm. Expand
Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes.
TLDR
The results suggest that the coumarin-type compounds in particular interact with the active sites of Cyp2a-5 and CYP2A6, and the active Sites are structurally different, since a number of compounds inhibited mouse, but not human COH activity. Expand
Bioactivity of certain Egyptian Ficus species.
TLDR
The fruit extracts of Ficus sycomorus, benjamina, bengalensis and religiosa had significant antibacterial activity, but no antifungal activity, which support the traditional use of these plants in folk medicine for respiratory disorders and certain skin diseases. Expand
Antimicrobial activity of some coumarin containing herbal plants growing in Finland.
TLDR
Sensitivity to methanol extracts was found to vary considerably among the micro-organisms, the extract from Petroselinum crispum and Ruta graveolens showing the highest toxicity against Rhizoctonia solani. Expand
Binding of phenolic compounds and their derivatives to bovine and reindeer beta-lactoglobulin.
TLDR
The binding of the aglycones of phenolic compounds to bovine and reindeer beta-lactoglobulins using fluorescence quenching implicated that betaLG could act as a binder or carrier for Phenolic compounds in acidic, basic, or neutral conditions and that the ligand/betaLG complex can remain stable during storage. Expand
Characterization of flavonoid--biomembrane interactions.
TLDR
There is an inverse correlation between the number of hydroxyl groups in the flavonoid and their capacity to induce calcein leakage through fluid EPC bilayer membranes (the more nonpolar flavonoids caused more calceIn leakage). Expand
Towards fabrication of 3D printed medical devices to prevent biofilm formation.
TLDR
This study demonstrates the incorporation of anti-microbial nitrofurantoin in a polymer carrier material and subsequent 3D printing of a model structure, which resulted in an inhibition of biofilm colonization. Expand
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