P. Vihko

Publications187
h-index52
Citations7,327
Highly Influential Citations260
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • R. Vihko
  • 313 Publications, 11,499 Citations
  • M. Poutanen
  • 279 Publications, 8,505 Citations
  • M. Zylka
  • 109 Publications, 9,624 Citations
  • H. Peltoketo
  • 62 Publications, 2,902 Citations
  • Publications
  • Influence
Prostatic Acid Phosphatase Is an Ectonucleotidase and Suppresses Pain by Generating Adenosine
Thiamine monophosphatase (TMPase, also known as fluoride-resistant acid phosphatase) is a classic histochemical marker of small-diameter dorsal root ganglia neurons. The molecular identity of TMPase… Expand
  • 152
  • 18
  • PDF
Colorectal carcinoma associated with serrated adenoma – prevalence, histological features, and prognosis
Serrated adenoma has been proposed to be a distinct entity among colorectal neoplasms. Progression to frank carcinoma has been suggested in individual cases, but the prevalence of carcinomas… Expand
  • 247
  • 14
Mutated human androgen receptor gene detected in a prostatic cancer patient is also activated by estradiol.
Androgens are necessary for the development of prostatic cancer. The mechanisms by which the originally androgen-dependent prostatic cancer cells are relieved of the requirement to use androgen for… Expand
  • 141
  • 10
Intracellular Machinery for Matrix Degradation in Bone‐Resorbing Osteoclasts
In osteoclasts, TRACP co‐localized with cathepsin K in transcytotic vesicles and was activated by cathepsin K in vitro, suggesting that TRACP may degrade organic matrix components in transcytotic… Expand
  • 139
  • 10
Intracellular Fragmentation of Bone Resorption Products by Reactive Oxygen Species Generated by Osteoclastic Tartrate-resistant Acid Phosphatase*
Tartrate-resistant acid phosphatase (TRAP) is highly expressed in bone-resorbing osteoclasts and activated macrophages. It has been suggested that a redox-active iron in the binuclear iron center of… Expand
  • 247
  • 9
Glycoproteins of the lysosomal membrane
Three glycoprotein antigens (120, 100, and 80 kD) were detected by mono- and/or polyclonal antibodies generated by immunization with highly purified rat liver lysosomal membranes. All of the antigens… Expand
  • 266
  • 8
  • PDF
Detection of hematogenous micrometastasis in patients with prostate cancer.
The goal of this study was to determine if patients with stage D0-3 prostatic adenocarcinoma have detectable hematogenous micrometastasis. Polymerase chain reaction amplification of prostate-specific… Expand
  • 385
  • 7
  • PDF
Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7.
17beta-Hydroxysteroid dehydrogenases (17HSDs) have a central role in the regulation of the biological activity of sex steroid hormones. There is increasing evidence that in addition to their… Expand
  • 119
  • 7
Molecular cloning of mouse 17 beta-hydroxysteroid dehydrogenase type 1 and characterization of enzyme activity.
The biological activity of certain estrogens and androgens is modulated by enzymes called 17 beta-hydroxysteroid dehydrogenases (17 beta-HSDs), which catalyze the interconversion between less active… Expand
  • 97
  • 6
Origin of Substrate Specificity of Human and Rat 17β-Hydroxysteroid Dehydrogenase Type 1, Using Chimeric Enzymes and Site-Directed Substitutions.
Human 17beta-hydroxysteroid dehydrogenase (17-HSD) type 1 predominantly catalyzes the 17beta-reduction of estrone to estradiol. The present results, however, show that rat 17-HSD type 1 equally uses… Expand
  • 66
  • 6