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Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men.
TLDR
An 8 week intensive training program inducing a marked reduction in abdominal fat and increase in insulin sensitivity does not affect adiponectin and leptin levels in men with type 2 diabetes. Expand
Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin: clinical pathophysiology and natural history of beta-cell dysfunction and insulin resistance.
TLDR
Ketosis-pronetype 2 diabetes can be distinguished from type 1 diabetes and classical type 2 diabetes by specific features of clinical pathophysiology and also by the natural history of beta-cell dysfunction and insulin resistance reflecting a propensity to glucose toxicity. Expand
Diabetes in Africans. Part 1: epidemiology and clinical specificities.
TLDR
The design and implementation of appropriate strategy for early diagnosis and treatment, and population-based primary prevention of diabetes in these high-risk populations is therefore a public health priority. Expand
Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-saharan africans.
TLDR
In this preliminary cross-sectional study, the presence of HHV-8 antibodies was associated with ketosis-prone DM-2 in patients of sub-Saharan African origin and longitudinal studies are required to understand the clinical significance of these findings. Expand
Effect of a diabetic environment in utero on predisposition to type 2 diabetes
TLDR
Exposure to a diabetic environment in utero is associated with increased occurrence of impaired glucose tolerance and a defective insulin secretory response in adult offspring, independent of genetic predisposition to type 2 diabetes. Expand
PAX4 gene variations predispose to ketosis-prone diabetes.
TLDR
Data provide the first evidence that ethnic-specific gene variants may contribute to the predisposition to this particular form of diabetes and suggest that KPD, like maturity onset diabetes of the young, is a rare, phenotypically defined but genetically heterogeneous form of type 2 diabetes. Expand
Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.
TLDR
A brief characterization of MSC immunomodulatory effects is provided, and the current experimental evidence for the potential therapeutic efficacy of M SC transplantation in diabetes is presented. Expand
Influence of migration on characteristics of type 2 diabetes in sub-Saharan Africans.
TLDR
The results suggest that Africans who emigrate to France may develop diabetes earlier than those staying in their home country, however, the latter may be a reflection of late diagnosis of diabetes. Expand
Diabetes in Africans. Part 2: Ketosis-prone atypical diabetes mellitus.
TLDR
The present review summarises the available clinical and metabolic features and suggests some pathogenetic hypotheses and principles of management for the ketosis-prone atypical diabetes of the Africans. Expand
Metabolic and immunogenetic prediction of long‐term insulin remission in African patients with atypical diabetes
TLDR
A cohort of ‘atypical’ diabetic patients of sub‐Saharan African origin is characterized and possible determinants of long‐term remission are analyzed to analyse possible determinant of long-term remission. Expand
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