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C-type virus particles in human tumours transplanted into nude mice.
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Development and validation of algorithms for the automatic detection of fretting based on multiple line texture data. Research into pavement surface disintegration. Phase 2 interim report
This report examines pavement condition, pavement maintenance, surface course texture, and the existence of fretting. It presents algorithms that would help identify the relevant variables, and aid
Isolation of infectious EB virus from the epithelial tumour cells of nasopharyngeal carcinoma
Lympho‐blastoid cell lines which express the EB virus nuclear antigen have been established from the transformed foetal lymphocytes, and thus carry the first isolate of the virus from the actual epithelial tumour cells of NPC, in a form suitable for further investigation.
Activation in vitro by BUdR of a productive eb virus infection in the epithelial cells of nasopharyngeal carcinoma
EB virus has thus, for the first time, been activated in NPC epithelial cells and shown to be capable of replication in a cell type other than a primate B‐lymphocyte.
Cytogenetics of malignant epithelial cells and lymphoblastoid cell lines from nasopharyngeal carcinoma.
The malignant epithelial cells of nasopharyngeal carcinoma (NPC) and cells of lines derived form the lymphoid cells which infiltrate this tumour have been investigated cytogenetically. Chromosome
Structure of diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase from Acinetobacter baumannii
The structure of a bifunctional deaminase/reductase involved in riboflavin biosynthesis in the pathogen A. baumannii has been determined in two crystal forms.
Abstract 222: Novel protein drug conjugates targeting ROR1 through the development and exploitation of a drug discovery platform based on small, engineered VNAR domains
High affinity binders to the extracellular domain of ROR1 are generated which show species cross-reactivity, do not bind the closely related family member ROR2, and can target distinct non-overlapping regions of the protein.
Engineering a surrogate human heteromeric α/β glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein
The development and characterization of a surrogate system to support drug discovery targeting a complex heteromeric human glycine receptor is described.