• Publications
  • Influence
Melatonin and serotonin effects on gastrointestinal motility.
TLDR
Melatonin is a promising therapeutic agent for IBS with activities independent of its effects on sleep, anxiety or depression and could be considered for prevention or treatment of colorectal cancer, ulcerative colitis, gastric ulcers and irritable bowel syndrome. Expand
Effects of vagal neuromodulation and vagotomy on control of food intake and body weight in rats.
TLDR
Results suggest that information in vagal afferents can be modulated resulting in changes of feeding behaviour and body weight as well as vagal nerve neuromodulation in control of food intake with fed-pattern microchip pacing. Expand
Relationships between duodenal motility and pancreatic secretion in fasted and fed dogs.
TLDR
It is concluded that the pancreatic secretion in fasted dogs fluctuates periodically in phase with duodenal motility, but the phase III peak secretory outputs represent only minute fractions of the maximal secretory capacity and can therefore be ignored in regular testing of Pancreatic secretion. Expand
Chronic impairment of the vagus nerve function leads to inhibition of dopamine but not serotonin neurons in rat brain structures.
TLDR
A close relationship between the peripheral vagus nerve impairment and the inhibition of dopamine system in the brain structures is suggested, the first report of such relationship which may suggest that mental changes could occur in the first stage of Parkinson's disease far ahead of motor impairment. Expand
Release of Cholecystokinin by Amino Acids
TLDR
The highest activity for release of CCK was exhibited by tryptophan and phenylalanine, which were also shown to release small amounts of secretin, which was 80% of the maximal response to exogenous CCK. Expand
Effects of nitric oxide on antral motility and gastric emptying in humans.
TLDR
Exogenous nitric oxide inhibits gastric emptying and antral motor activity, which could be useful in the treatment of patients with functional disturbances of gastric motility and emptying; and the reduction in gastric emptied and motility observed after the administration of L-arginine results from changes in plasma enterohormone release rather than from the enhanced formation of endogenous nitricoxide. Expand
Effect of long-term vagal stimulation on food intake and body weight during diet induced obesity in rats.
TLDR
Data support theory that VNS can increase vagal afferent signal conduct to CNS and mimics the satiety signals leading to reduce food intake and body weight gain, and support the role of electrical VNS in long-term control in diet induced obesity fed rats. Expand
Role of cholecystokinin in the control of gastric emptying and secretory response to a fatty meal in normal subjects and duodenal ulcer patients.
TLDR
It is indicated that endogenous CCK released by a fatty meal delays gastric emptying and inhibits gastric acid and plasma gastrin responses in healthy subjects, but in duodenal ulcer patients the inhibitory effect of CCK is less pronounced, suggesting a defect in the action of this hormone on gastrin release and Gastric acid secretion. Expand
Nitric oxide inhibits the myoelectric activity of the small intestine in dogs.
TLDR
It is concluded that NO system exerts a tonic inhibitory influence on intestinal myoelectric activity by reducing the frequency of MMC pacesetter and by suppressing the postprandial spike activity. Expand
Magnetic field anti-inflammatory effects in Crohn's disease depends upon viability and cytokine profile of the immune competent cells.
TLDR
The electromagnetically induced cell death could be an important step for non-invasive PEMF treatment in chronic inflammatory diseases. Expand
...
1
2
3
4
5
...