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Dynamic mapping of human cortical development during childhood through early adulthood.
TLDR
The dynamic anatomical sequence of human cortical gray matter development between the age of 4-21 years using quantitative four-dimensional maps and time-lapse sequences reveals that higher-order association cortices mature only after lower-order somatosensory and visual cortices are developed. Expand
Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration
TLDR
This study is the largest evaluation of nonlinear deformation algorithms applied to brain image registration ever conducted and suggests that the findings are generalizable to new subject populations that are labeled or evaluated using different labeling protocols. Expand
Mapping cortical change across the human life span
TLDR
A significant, nonlinear decline in GMD with age is found over dorsal frontal and parietal association cortices on both the lateral and interhemispheric surfaces, indicating that the posterior temporal cortices have a more protracted course of maturation than any other cortical region. Expand
Sexual dimorphism of brain developmental trajectories during childhood and adolescence
TLDR
This largest longitudinal pediatric neuroimaging study reported to date demonstrates the importance of examining size-by-age trajectories of brain development rather than group averages across broad age ranges when assessing sexual dimorphism and finds robust male/female differences in the shapes of trajectories. Expand
Longitudinal Mapping of Cortical Thickness and Brain Growth in Normal Children
TLDR
For the first time, developmental changes in gray matter thickness, brain size, and structure-function relationships have been traced within the same individuals studied longitudinally during a time of rapid cognitive development. Expand
The clinical use of structural MRI in Alzheimer disease
TLDR
The utility of structural imaging and other markers will be increased by standardization of acquisition and analysis methods, and by development of robust algorithms for automated assessment, as well as by research into other imaging and nonimaging markers. Expand
Mapping brain asymmetry
TLDR
Brain-mapping approaches show great promise for assessing factors that modulate cognitive specialization in the brain, including the ontogeny, phylogeny and genetic determinants of brain asymmetry. Expand
Dynamics of Gray Matter Loss in Alzheimer's Disease
TLDR
This degenerative sequence, observed in vivo as it developed, provides the first quantitative, dynamic visualization of cortical atrophic rates in normal elderly populations and in those with dementia. Expand
Robust Brain Extraction Across Datasets and Comparison With Publicly Available Methods
TLDR
This paper introduces a robust, learning-based brain extraction system (ROBEX), which combines a discriminative and a generative model to achieve the final result and shows that ROBEX provides significantly improved performance measures for almost every method/dataset combination. Expand
In vivo evidence for post-adolescent brain maturation in frontal and striatal regions
TLDR
The pattern of brain maturation during these years was distinct from earlier development, and was localized to large regions of dorsal, medial and orbital frontal cortex and lenticular nuclei, with relatively little change in any other location. Expand
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