• Publications
  • Influence
PubChem Substance and Compound databases
TLDR
An overview of the PubChem Substance and Compound databases, including data sources and contents, data organization, data submission using PubChem Upload, chemical structure standardization, web-based interfaces for textual and non-textual searches, and programmatic access. Expand
  • 1,726
  • 94
CDD: a Conserved Domain Database for protein classification
TLDR
The Conserved Domain Database (CDD) is the protein classification component of NCBI's Entrez query and retrieval system. Expand
  • 1,151
  • 93
  • PDF
PubChem: Integrated Platform of Small Molecules and Biological Activities
TLDR
PubChem is an open repository for experimental data identifying the biological activities of small molecules. Expand
  • 979
  • 75
CDD: a database of conserved domain alignments with links to domain three-dimensional structure
TLDR
The Conserved Domain Database (CDD) is a compilation of multiple sequence alignments representing protein domains conserved in molecular evolution. Expand
  • 630
  • 66
  • PDF
CDD: a curated Entrez database of conserved domain alignments
TLDR
The Conserved Domain Database (CDD) is now indexed as a separate database within the Entrez system and linked to other Entrez databases such as MEDLINE(R). Expand
  • 759
  • 48
  • PDF
PubChem 2019 update: improved access to chemical data
TLDR
We provide an update on the three PubChem databases since the previous papers, as well as the release of new web interfaces. Expand
  • 595
  • 29
  • PDF
PubChem BioAssay: 2017 update
  • Y. Wang, S. Bryant, +6 authors Jian Zhang
  • Biology, Medicine
  • Nucleic Acids Res.
  • 28 November 2016
TLDR
PubChem's BioAssay database (https://pubchem.ncbi.nlm.nih.gov) has served as a public repository for small-molecule and RNAi screening data. Expand
  • 177
  • 14
  • PDF
MMDB and VAST+: tracking structural similarities between macromolecular complexes
TLDR
The computational detection of similarities between protein 3D structures has become an indispensable tool for the detection of homologous relationships, the classification of protein families and functional inference. Expand
  • 175
  • 9
  • PDF
MMDB: Entrez's 3D-structure database
TLDR
Three-dimensional structures are now known within many protein families and it is quite likely, in searching a sequence database, that one will encounter a homolog with known structure. Expand
  • 183
  • 6
MMDB: annotating protein sequences with Entrez's 3D-structure database
TLDR
We present an annotation service that combines some of these tools automatically, Entrez's ‘Related Structure’ links, with the Molecular Modeling Database (MMDB), a 3D-structure database. Expand
  • 109
  • 6
  • PDF