• Publications
  • Influence
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
TLDR
Management of HUS remains supportive; there are no specific therapies to ameliorate the course, and the best way to prevent HUS is to prevent primary infection with Shiga-toxin-producing bacteria. Expand
Practice guidelines for the management of infectious diarrhea.
TLDR
Prevention by avoidance of undercooked meat or seafood, avoidance of unpasteurized milk or soft cheese, and selected use of available typhoid vaccines for travelers to areas where typhoid is endemic are key to the control of infectious diarrhea. Expand
Enterohaemorrhagic Escherichia coli in human medicine.
TLDR
This review will focus on the microbiology, epidemiology, and pathophysiology of EHEC-associated diseases, and illustrate future challenges and opportunities for their control. Expand
The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections.
TLDR
Antibiotic treatment of children with E. coli O157:H7 infection increases the risk of the hemolytic-uremic syndrome, and antibiotic administration remained a risk factor for the development of the Hemolytic uremic syndrome. Expand
Toxin genotypes and plasmid profiles as determinants of systemic sequelae in Escherichia coli O157:H7 infections.
TLDR
This study shows that E. coli O157:H7 isolates systematically collected from a single geographic region over a defined time period exhibit considerable diversity in plasmid content and toxin genotypes and that the toxin genotype of the infecting strain may influence the risk of developing microangiopathic sequelae. Expand
The prevalence of Escherichia coli O157.H7 in dairy and beef cattle in Washington State.
TLDR
Faecal/urine slurry samples, bulk milk samples, and milk filters from dairy herds were negative for E. coli O157.H7, suggesting the possibility that human E. H7 exposure may be reduced by cattle management procedures. Expand
Escherichia coli O157:H7 Shiga Toxin-Encoding Bacteriophages: Integrations, Excisions, Truncations, and Evolutionary Implications
TLDR
The unexpected diversity of the chromosomal architecture of E. coli O157:H7 is demonstrated, suggesting that stx(1) acquisition might be a multistep process, and the consideration of multiple exogenous factors, including antibiotics and bile, when chromosome stability is examined. Expand
A longitudinal study of Escherichia coli O157 in fourteen cattle herds.
TLDR
For all herds the highest prevalence occurred in the summer months, which resulted in most of the positive faecal samples being collected on a minority of sampling visits. Expand
A multistate outbreak of Escherichia coli O157:H7-associated bloody diarrhea and hemolytic uremic syndrome from hamburgers. The Washington experience.
TLDR
This E coli O157:H7 outbreak, the largest reported, resulted from errors in meat processing and cooking and measures should be developed to reduce meat contamination. Expand
Escherichia coli O157:H7: clinical, diagnostic, and epidemiological aspects of human infection.
  • P. Tarr
  • Medicine
  • Clinical infectious diseases : an official…
  • 1995
TLDR
Research should be directed at reducing the carriage of E. coli O157:H7 at its bovine source, minimizing the microbial content of food and water, and averting systemic microangiopathic hemolytic anemia after infection with this pathogen. Expand
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