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Chemoprevention of colorectal cancer: systematic review and economic evaluation.
BACKGROUND Colorectal cancer (CRC) is the third most common cancer in the UK: incidence increases with age, median age at diagnosis being over 70 years. Approximately 25% of cases occur in… Expand
Modelling the cost effectiveness of interferon beta and glatiramer acetate in the management of multiple sclerosis. Commentary: evaluating disease modifying treatments in multiple sclerosis.
Abstract Objective: To evaluate the cost effectiveness of four disease modifying treatments (interferon betas and glatiramer acetate) for relapsing remitting and secondary progressive multiple… Expand
A systematic review and economic evaluation of exercise referral schemes in primary care: a short report.
- F. Campbell, Mike Holmes, +5 authors E. Kaltenthaler
- Health technology assessment
- 29 July 2015
BACKGROUND It is estimated that only 39% of men and 29% of women in England achieve the levels of physical activity that are recommended to protect health and prevent disease. One approach to… Expand
A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models.
Background: Multiple sclerosis (MS) is a progressive degenerative disease of the CNS with a pattern of symptoms that depends on the type of disease and the site of lesions. As damage… Expand
Option appraisal of population-based colorectal cancer screening programmes in England
Objectives: To estimate the effectiveness, cost-effectiveness and resource impact of faecal occult blood testing (FOBT) and flexible sigmoidoscopy (FSIG) screening options for colorectal cancer to… Expand
Systematic review and economic evaluation of bevacizumab and cetuximab for the treatment of metastatic colorectal cancer.
OBJECTIVES To assess the clinical effectiveness and cost-effectiveness of bevacizumab and cetuximab in the treatment of individuals with metastatic colorectal cancer (CRC). DATA SOURCES Searches of… Expand
The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer: systematic review and economic evaluation.
- D. Hind, P. Tappenden, I. Tumur, S. Eggington, P. Sutcliffe, A. Ryan
- Health technology assessment
- 1 May 2008
OBJECTIVES To evaluate three technologies for the management of advanced colorectal cancer: (1) first-line irinotecan combination [with 5-fluorouracil (5-FU)] or second-line monotherapy; (2) first-… Expand
Avoiding and identifying errors in health technology assessment models: qualitative study and methodological review.
BACKGROUND Health policy decisions must be relevant, evidence-based and transparent. Decision-analytic modelling supports this process but its role is reliant on its credibility. Errors in… Expand
Cost-effectiveness of disease-modifying therapies in the management of multiple sclerosis for the Medicare population.
- P. Tappenden, C. McCabe, +5 authors Murray L. Brown
- Value in health : the journal of the…
- 1 July 2009
OBJECTIVE To evaluate the cost-effectiveness of disease-modifying therapies (DMTs) for the management of multiple sclerosis (MS) compared to best supportive care in the United States. METHODS… Expand
A review and critique of modelling in prioritising and designing screening programmes.
OBJECTIVES To undertake a structured review and critical appraisal of methods for the model-based cost-utility analysis of screening programmes. Also to develop guidelines and an assessment checklist… Expand