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Chemoprevention of colorectal cancer: systematic review and economic evaluation.
BACKGROUND Colorectal cancer (CRC) is the third most common cancer in the UK: incidence increases with age, median age at diagnosis being over 70 years. Approximately 25% of cases occur inExpand
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Modelling the cost effectiveness of interferon beta and glatiramer acetate in the management of multiple sclerosis. Commentary: evaluating disease modifying treatments in multiple sclerosis.
Abstract Objective: To evaluate the cost effectiveness of four disease modifying treatments (interferon betas and glatiramer acetate) for relapsing remitting and secondary progressive multipleExpand
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A systematic review and economic evaluation of exercise referral schemes in primary care: a short report.
BACKGROUND It is estimated that only 39% of men and 29% of women in England achieve the levels of physical activity that are recommended to protect health and prevent disease. One approach toExpand
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A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models.
Background: Multiple sclerosis (MS) is a progressive degenerative disease of the CNS with a pattern of symptoms that depends on the type of disease and the site of lesions. As damageExpand
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Option appraisal of population-based colorectal cancer screening programmes in England
Objectives: To estimate the effectiveness, cost-effectiveness and resource impact of faecal occult blood testing (FOBT) and flexible sigmoidoscopy (FSIG) screening options for colorectal cancer toExpand
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Systematic review and economic evaluation of bevacizumab and cetuximab for the treatment of metastatic colorectal cancer.
OBJECTIVES To assess the clinical effectiveness and cost-effectiveness of bevacizumab and cetuximab in the treatment of individuals with metastatic colorectal cancer (CRC). DATA SOURCES Searches ofExpand
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The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer: systematic review and economic evaluation.
OBJECTIVES To evaluate three technologies for the management of advanced colorectal cancer: (1) first-line irinotecan combination [with 5-fluorouracil (5-FU)] or second-line monotherapy; (2) first-Expand
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Avoiding and identifying errors in health technology assessment models: qualitative study and methodological review.
BACKGROUND Health policy decisions must be relevant, evidence-based and transparent. Decision-analytic modelling supports this process but its role is reliant on its credibility. Errors inExpand
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Cost-effectiveness of disease-modifying therapies in the management of multiple sclerosis for the Medicare population.
OBJECTIVE To evaluate the cost-effectiveness of disease-modifying therapies (DMTs) for the management of multiple sclerosis (MS) compared to best supportive care in the United States. METHODSExpand
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A review and critique of modelling in prioritising and designing screening programmes.
OBJECTIVES To undertake a structured review and critical appraisal of methods for the model-based cost-utility analysis of screening programmes. Also to develop guidelines and an assessment checklistExpand
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