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Overexpression and characterization of recombinant human fusion protein IL‐6/IL‐2 (ch925)
The studies exhibited that CH925 exerted a significant augmentative effect on the growth of erythroid colony forming units (CFU‐E), and synergized with erythropoietin (EPO) and/or IL‐3 in a dose‐dependent way. Expand
Erythropoietin-like activity in vivo of the fusion protein rhIL-6/IL-2 (CH925).
The reticulocyte response was observed in transfusion-induced polycythemic mice by using flow cytometry with pyronin Y staining, and activity of CH925 (100 micrograms/kg/d) corresponds to 1 U of standard rhEpo in the authors' study. Expand
Expression of human interleukin-11 cDNA in E. coli.
  • J. Miao, J. Wang, +5 authors X. Ma
  • Chemistry, Medicine
  • Science in China. Series B, Chemistry, life…
  • 1 October 1995
A 551-bp hIL-11 gene fragment that includes no nucleotide sequences encoding signal polypeptide and the initial 8 amino acids of the mature protein was cloned into a high-level expression vector pEx31B of E. coli and expression in the PL promoter system, which is temperature-regulated, was achieved. Expand
The role of recombinant human fusion protein IL-6/IL-2 (CH925) in hepadna virus infection treatment.
It is suggested that CH925 might be a potential remedy in HBV infection treatment. Expand
Direct Western Blot Detection of HA Epitope-Tagged Proteins Using Anti-HA-Peroxidase
conjugate of Anti-HA monoclonal antibody and the reporter enzyme horseradish per- oxidase, for direct detection of HA-tagged fusion proteins in western blot analyses. Use of Anti-HA-peroxidaseExpand