P. Taghert

Publications125
h-index57
Citations9,829
Highly Influential Citations840
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A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila.
View on Elsevier
A pdf Neuropeptide Gene Mutation and Ablation of PDF Neurons Each Cause Severe Abnormalities of Behavioral Circadian Rhythms in Drosophila
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Widespread Receptivity to Neuropeptide PDF throughout the Neuronal Circadian Clock Network of Drosophila Revealed by Real-Time Cyclic AMP Imaging
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Drosophila MEF2, a transcription factor that is essential for myogenesis.
TLDR
It is shown that the Drosophila MEF2 protein is expressed throughout the mesoderm following gastrulation and required for later aspects of differentiation of the three major types of musculature, which include body wall muscles, gut musculatures, and the heart, in the Dosophila embryo.
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Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome.
TLDR
The recently completed Drosophila genome sequence for G protein-coupled receptors sensitive to bioactive peptides (peptide GPCRs) is scanned and 44 genes are described that represent the vast majority, and perhaps all, of the peptide G PCRs encoded in the fly genome.
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The Neuropeptide Pigment-Dispersing Factor Coordinates Pacemaker Interactions in the Drosophila Circadian System
TLDR
Time-series immunostainings for the PERIOD protein in normal and pdf mutant flies over 9 d of constant conditions suggest that pdf is not required to maintain circadian protein oscillations under constant conditions; however, it is required to coordinate the phase and amplitude of such rhythms among the diverse pacemakers.
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PDF Receptor Signaling in Drosophila Contributes to Both Circadian and Geotactic Behaviors
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Genetic analysis of the Drosophila ellipsoid body neuropil: organization and development of the central complex.
TLDR
The development of the ellipsoid body neuropil in wild-type animals is described and developmental mechanisms based on animals displaying structural mutations of this neuroppil are proposed, which suggest functional classifications as well.
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Reevaluation of Drosophila melanogaster's neuronal circadian pacemakers reveals new neuronal classes
TLDR
An enhancer trap marker called R32 is described that specifically reveals several previously undescribed aspects of the fly's central neuronal pacemakers, and it is shown that the neuropeptide IPNamide is specifically expressed by this DN1 subclass, which implicateIPNamide as a second candidate circadian transmitter in the Drosophila brain.
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The bHLH protein Dimmed controls neuroendocrine cell differentiation in Drosophila
TLDR
It is proposed that dimmed encodes an integral component of a novel mechanism by which diverse neuroendocrine lineages differentiate and maintain the pro-secretory state.
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