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Environmentally induced variation in diterpene composition of the marine sponge Rhopaloeides odorabile
Field experiments in which fragments of one individual sponge were transplanted to different conditions of illumination and depth demonstrate that the chemical variability reflects the range of environmental conditions under which R. odorabile lives rather than any genetic differences. Expand
The distribution of brominated long-chain fatty acids in sponge and symbiont cell types from the tropical marine spongeAmphimedon terpenensis
The association of brominated long-chain fatty acids (LCFA) with sponge cells has been confirmed and the findings allow comment on the use of fatty acid profiles in chemotaxonomy and permit further interpretation of LCFA biosynthetic pathways in sponges. Expand
Terpenes in sponge cell membranes: Cell separation and membrane fractionation studies with the tropical marine spongeAmphimedon sp.
The differing sponge and symbiotic microbial cell types in the tropical marine spongeAmphimedon sp. were fractionated according to density, investigated by electron microscopy, and analyzed byExpand
Candidaspongiolides, distinctive analogues of tedanolide from sponges of the genus Candidaspongia.
The candidaspongiolide mixture was potently cytotoxic, exhibiting a mean panel 50% growth inhibition (GI50) of 14 ng/mL in the National Cancer Institute's 60-cell-line in vitro antitumor screen. Expand
Chemotaxonomic relationships within, and comparisons between, the orders Haplosclerida and Petrosida (Porifera: Demospongiae) using sterol complements
The results of this study did not support separation of sponge species into the two orders, Haplosclerida and Petrosida, on the basis of sterol complements, suggesting either their taxonomic allocations at this level are incorrect, or sterol complement is not a useful feature at this taxonomic level. Expand
Microxine, a new cdc2 kinase inhibitor from the Australian marine sponge Microxina species.
A new purine derivative microxine (1) was isolated from the Australian marine sponge Microxina sp. The compound was isolated via reversed-phase chromatography and its structure determinedExpand
Halogenated Pyrrolo(2,3-dlpyrimidine Nucleosides from Marine Organisms
The pharmacologically active constituent of the red alga Hypnea valendiae has been identified as 4-amino-7-(5'-deoxyribos-1'~-yl)-5-iodopyrrolo(2,3-d)pyrimidine (7). a second nucleoside, tentatively assigned as the l'a isomer of (7), has been isolated. Expand
Echinoclasterol sulfate phenethylammonium salt, a unique steroid sulfate from the marine sponge, Echinoclathria subhispida
Abstract A phenethylammonium salt of a new steroid sulfate, echinoclasterol sulfate (1) has been isolated from the marine sponge, Echinoclathria subhispida. The structure was determined byExpand
The distribution of lipids and sterols in cell types from the marine spongePseudaxinyssa sp
The spongePseudaxinyssa sp., unique in sterol and fatty acid composition, was cellularly dissected into fractions enriched in each of the major cell types present in the sponge: microbial symbiontsExpand
Octa- and nonaprenylhydroquinone sulfates, inhibitors of alpha1,3-fucosyltransferase VII, from an Australian marine sponge Sarcotragus sp.
Two inhibitors of Fuc TVII from a marine sponge Sarcotragus sp. Expand