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The costs of production of alternative jet fuel: A harmonized stochastic assessment.
This study quantifies and compares the costs of production for six alternative jet fuel pathways using consistent financial and technical assumptions. Uncertainty was propagated through the analysisExpand
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Flex ddG: Rosetta ensemble-based estimation of changes in protein-protein binding affinity upon mutation
Computationally modeling changes in binding free energies upon mutation (interface ΔΔG) allows large-scale prediction and perturbation of protein-protein interactions. Additionally, methods thatExpand
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Life Cycle Greenhouse Gas Emissions and Costs of Production of Diesel and Jet Fuel from Municipal Solid Waste.
This paper quantifies and compares the life cycle GHG emissions and costs of production of diesel and jet fuel derived from municipal solid waste (MSW) in the United States via three thermochemicalExpand
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Flex ddG: Rosetta Ensemble-Based Estimation of Changes in Protein-Protein Binding Affinity upon Mutation.
Computationally modeling changes in binding free energies upon mutation (interface ΔΔ G) allows large-scale prediction and perturbation of protein-protein interactions. Additionally, methods thatExpand
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Structure‐based simulations reveal concerted dynamics of GPCR activation
G protein‐coupled receptors (GPCRs) are a vital class of proteins that transduce biological signals across the cell membrane. However, their allosteric activation mechanism is not fully understood;Expand
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The Spindle: Integrating Architecture and Mechanics across Scales.
The spindle segregates chromosomes at cell division, and its task is a mechanical one. While we have a nearly complete list of spindle components, how their molecular-scale mechanics give rise toExpand
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Aviation CO2 emissions reductions from the use of alternative jet fuels
Abstract Although a relatively small contributor to annual anthropogenic CO2 emissions (~2.6%), commercial aviation activity is growing at ~5% per annum. As a result, alternative jet fuel (AJF)Expand
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Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance
ABSTRACT Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection experiments performed in theExpand
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Congenital Pulmonary Airway Malformation – 19-Year Experience from a Tertiary Care Center in India
Abstract Background: Congenital pulmonary airway malformation (CPAM) is a collection of non-hereditary, developmental anomalies. Our aim was to analyze the histological profiles and prevalence ofExpand
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qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps.
Proteins and ligands sample a conformational ensemble that governs molecular recognition, activity, and dissociation. In structure-based drug design, access to this conformational ensemble isExpand
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