P. Supavilai

Publications31
h-index18
Citations1,077
Highly Influential Citations14
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Dopamine D2 receptors in the rat brain: autoradiographic visualization using a high-affinity selective agonist ligand
The non-catechol, selective dopamine D2-agonist compound 3H-205–502 was used to localize dopamine D2 receptors by autoradiography after in vitro labeling of brain sections. The characteristics of the… Expand
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Modulation of GABA binding sites by CNS depressants and CNS convulsants
[(3)H]Muscimol binding at 23 degrees C and muscimol stimulated [(3)H]flunitrazepam binding at 37 degrees C to membranes of rat cerebral cortex have been investigated. In washed membrane preparations,… Expand
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Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
GABA, THIP and muscimol enhance spontaneous and inhibit electrically induced release of tritium labelled compounds from rat striatal slices which have been pre-labelled with 3H-choline. Baclofen is… Expand
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[35S]-t-butylbicyclophosphorothionate binding sites are constituents of the gamma-aminobutyric acid benzodiazepine receptor complex
t- Butylbicyclophosphorothionate ( TBPS ), a derivative of potent GABA antagonistic cage convulsants, has recently been introduced ( Squires , R. F., J.E. Casida , M. Richardson, and E. Saederup… Expand
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Interaction of SQ 20009 and GABA-like drugs as modulators of benzodiazepine receptor binding.
SQ 20009, a new anxiolytic drug structurally unrelated to GABA or benzodiazepines, has two modulatory effects on the binding of 3H-flunitrazepam to membranes from rat cerebellum. Thus, SQ 20009 has a… Expand
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Action of pyrazolopyridines as modulators of [3H]flunitrazepam binding to the gaba/benzodiazepine receptor complex of the cerebellum.
The pyrazolopyridines etazolate (SQ 20009) and cartazolate (SQ 65396) have strong modulatory effects on the GABA/benzodiazepine receptor complex of rate cerebellum. Thus, etazolate and cartazolate… Expand
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Differential modulation of [35S]TBPS binding by the occupancy of benzodiazepine receptors with its ligands.
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Anion-dependent modulation of [3H]muscimol binding and of GABA-stimulated [3H]flunitrazepam binding by picrotoxin and related CNS convulsants.
Picrotoxin, isopropylbicyclophosphate (IPTBO) and related CNS-convulsants have allosteric effects on the binding of ligands to the GABA/benzodiazepine receptor complex. When binding experiments were… Expand
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Calcium antagonist binding sites in the rat brain: Quantitative autoradiographic mapping using the 1,4-dihydropyridines [3H]PN 200-110 and [3H]PY 108-068
Anin vitro autoradiographic technique has been used for the quantitative mapping of calcium antagonist binding sites (CABS) in the rat brain, using the 1,4-dihydropyridines [3H]PN 200-110 and [3H]PY… Expand
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Stimulation of benzodiazepine receptor binding by SQ 20009 is chloride-dependent and picrotoxin-sensitive.
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