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Cytotoxic sterols from the formosan brown alga Turbinaria ornata.
TLDR
Sterols 1, 2, and 4 exhibited cytotoxicity against various cancer cell lines and were converted into 29-hydroxystigmasta-5,24 (28)-dien-3beta-ol by reaction with LAH.
Neuroprotection by marine-derived compound, 11-dehydrosinulariolide, in an in vitro Parkinson’s model: a promising candidate for the treatment of Parkinson’s disease
TLDR
It is concluded that 11-dehydrosinulariolide is a promising candidate for the treatment of Parkinson’s disease through its anti-apoptotic and anti-inflammatory action via PI3K signaling.
Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence
TLDR
Experimental evidence suggests that herbal extracts such as Solanum nigrum and Claviceps purpurea and isolated herbal compounds combined with antitumoral drugs have the potential to attenuate resistance against cancer therapy and to exert chemoprotective actions.
Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory activity of imperatorin from Glehnia littoralis.
TLDR
Results suggested that imperatorin had anti-inflammatory effects in LPS-stimulated RAW 264.7 cells and Carr-injected mice, respectively, and inhibition of elevated iNOS and COX-2 protein expression as well as neutrophil infiltration of Carr- injected paws may be involved in the beneficial effects of Imperatorin.
Terpenoids from the Soft Coral Sinularia sp. Collected in Yongxing Island
Three new sesquiterpenoids (sinuketal (1), sinulins A and B (2 and 3)) and two new cembranoids (sinulins C and D (4 and 5)), as well as eight known sesquiterpenoids (6–13) and eight known cembranoids
Meroditerpenoids from a Formosan soft coral Nephthea chabrolii.
TLDR
Eight new meroditerpenoid-related metabolites, including one naphthoquinone derivative, chabrolonaphthOquinone B, and four tetraprenyltoluquinone-related compounds, chABrolobenzoquinones E-H, were isolated from the organic extract of a Taiwanese soft coral Nephthea chabroii.
Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice.
TLDR
The present study suggests that the anti-inflammatory mechanisms of TR1 and TR2 might be related to the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity.
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