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Long-term persistence of hormonal adaptations to weight loss.
BACKGROUND After weight loss, changes in the circulating levels of several peripheral hormones involved in the homeostatic regulation of body weight occur. Whether these changes are transient orExpand
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Ketosis and appetite-mediating nutrients and hormones after weight loss
Background/Objectives:Diet-induced weight loss is accompanied by compensatory changes, which increase appetite and encourage weight regain. There is some evidence that ketogenic diets suppressExpand
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The effect of rate of weight loss on long-term weight management: a randomised controlled trial.
BACKGROUND Guidelines recommend gradual weight loss for the treatment of obesity, indicative of a widely held opinion that weight lost rapidly is more quickly regained. We aimed to investigate theExpand
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The defence of body weight: a physiological basis for weight regain after weight loss.
Although weight loss can usually be achieved by restricting food intake, the majority of dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the gastrointestinalExpand
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Review of 3‐year outcomes of a very‐low‐energy diet‐based outpatient obesity treatment programme
Obesity is a complex disorder that requires a multidisciplinary treatment approach. This review evaluated 3‐year outcomes of a very‐low‐energy diet (VLED)‐based programme at a tertiary hospitalExpand
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Treatment of obesity in older persons-A systematic review.
The study aims to systematically review the available evidence regarding weight loss interventions (lifestyle, surgical, and pharmacological) for obesity in adults aged over 60 years. A search ofExpand
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Ketogenic diets for weight loss: A review of their principles, safety and efficacy.
SUMMARY Low-carbohydrate "ketogenic" diets have increased in popularity over recent years as a means of weight loss. Published studies of these diets have been highly heterogeneous, and it remainsExpand
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The rate of weight loss does not influence long term weight maintenance: A randomised controlled trial
tive online surveys were conducted in Australian adults (n = 1635, 810 males) and General Practitioners (GPs) (n = 300, 180 males) in March and April 2014, respectively, to understand nutritionExpand
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Benefit-Risk Assessment of Orlistat in the Treatment of Obesity
Orlistat, an inhibitor of intestinal lipase, has been available for the treatment of obesity for nearly two decades. In conjunction with a hypocaloric diet, orlistat treatment results in aExpand
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