• Publications
  • Influence
Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells
TLDR
The study reveals hitherto unknown complexity of neural stem cell polarity, differential Golgi contribution to their specific architecture, and fundamental Golgi re-organization upon cell fate change in mouse aRGs.
Iron expulsion by exosomes drives ferroptosis resistance
  • P. Strzyz
  • Biology
    Nature Reviews Molecular Cell Biology
  • 20 November 2019
Exosomes are a route for expelling iron out of cells exposed to ferroptotic stimuli, thereby protecting them from ferroptotic cell death.
AMPK against NASH
  • P. Strzyz
  • Medicine
    Nature Reviews Molecular Cell Biology
  • 18 February 2020
A new study in Science shows that AMPK is an inhibitor of caspase 6-driven hepatic cell death in non-alcoholic steatohepatitis.
CRISPR-Cas9 wins Nobel.
  • P. Strzyz
  • Medicine
    Nature reviews. Molecular cell biology
  • 13 October 2020
Transcription: No proper rest in mitosis
  • P. Strzyz
  • Biology
    Nature Reviews Molecular Cell Biology
  • 4 October 2017
Low-level transcription persists during mitosis, and the reinstatement of robust gene expression occurs in a stepwise manner, starting with genes regulating cell organization and growth followed by
Cell Death: Molecular insights into execution of necroptosis
  • P. Strzyz
  • Biology
    Nature Reviews Molecular Cell Biology
  • 17 February 2016
TLDR
A model in which MLKL sequentially engages with the plasma membrane for necroptosis execution is proposed, in which it first oligomerizes through interactions in a region known as the brace, then interaction of the protein N-terminal helix bundle with membranous phosphatidylinositols.
STINGing revelations
  • P. Strzyz
  • Psychology
    Nature Reviews Molecular Cell Biology
  • 2019
Four studies provide new insights into the mechanism, functions and regulation of the cGAS–STING pathway.
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