• Publications
  • Influence
A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.
The recent research findings concerning syndromes of muscle wasting, malnutrition, and inflammation in individuals with chronic kidney disease (CKD) or acute kidney injury (AKI) have led to a needExpand
  • 1,185
  • 95
  • Open Access
Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure.
BACKGROUND Atherosclerotic cardiovascular disease and malnutrition are widely recognized as leading causes of the increased morbidity and mortality observed in uremic patients. C-reactive proteinExpand
  • 1,540
  • 48
The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia.
Cardiovascular disease is the leading cause of mortality in uremic patients. In large cross-sectional studies of dialysis patients, traditional cardiovascular risk factors such as hypertension andExpand
  • 1,023
  • 41
  • Open Access
Review on uremic toxins: classification, concentration, and interindividual variability.
BACKGROUND The choice of the correct concentration of potential uremic toxins for in vitro, ex vivo, and in vivo experiments remains a major area of concern; errors at this level might result inExpand
  • 1,112
  • 40
  • Open Access
Oxidative stress in end-stage renal disease: an emerging threat to patient outcome.
INTRODUCTION Patients affected by end-stage renal disease (ESRD) experience an excess of morbidity and mortality due to cardiovascular disease (CVD), which cannot be fully explained by the classicalExpand
  • 647
  • 30
  • Open Access
IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly.
It has been increasingly apparent that wasting and cardiovascular disease (CVD) is associated with a persistent systemic inflammatory response in end-stage renal disease (ESRD) patients. The reasonsExpand
  • 701
  • 30
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle?
Premature cardiovascular disease (CVD), including stroke, peripheral vascular disease, sudden death, coronary artery disease, and congestive heart failure, is a notorious problem in patients withExpand
  • 485
  • 25
  • Open Access
Aspects of immune dysfunction in end-stage renal disease.
End-stage renal disease (ESRD) is associated with significantly increased morbidity and mortality resulting from cardiovascular disease (CVD) and infections, accounting for 50% and 20%, respectively,Expand
  • 502
  • 21
  • Open Access
Review Articles: Inflammation in End‐stage Renal Disease: Sources, Consequences, and Therapy
Cardiovascular disease (CVD) remains the main cause of morbidity and mortality in patients with end‐stage renal disease (ESRD). Although traditional risk factors are common in ESRD patients, theyExpand
  • 391
  • 20
Are there two types of malnutrition in chronic renal failure? Evidence for relationships between malnutrition, inflammation and atherosclerosis (MIA syndrome).
Many methods have been used to assess the presence It is believed that malnutrition is common in patients with chronic renal failure (CRF). They have reduced of malnutrition in patients with CRF. AExpand
  • 716
  • 19