Heart rate variability: a measure of cardiac autonomic tone.
- P. Stein, M. Bosner, R. Kleiger, B. M. Conger
- MedicineAmerican Heart Journal
- 1 May 1994
Heart Rate Variability: Measurement and Clinical Utility
- R. Kleiger, P. Stein, J. Bigger
- MedicineAnnals of Noninvasive Electrocardiology
- 1 January 2005
Electrocardiographic RR intervals fluctuate cyclically, modulated by ventilation, baroreflexes, and other genetic and environmental factors that are mediated through the autonomic nervous system, and are useful for assessing risk of cardiovascular death or arrhythmic events, especially when combined with other tests.
Depression, Heart Rate Variability, and Acute Myocardial Infarction
- R. Carney, J. Blumenthal, K. Freedland
- Medicine, PsychologyCirculation
- 23 October 2001
It is concluded that greater autonomic dysfunction, as reflected by decreased HRV, is a plausible mechanism linking depression to increased cardiac mortality in post-MI patients.
RR variability in healthy, middle-aged persons compared with patients with chronic coronary heart disease or recent acute myocardial infarction.
- J. Bigger, J. Fleiss, R. Steinman, L. Rolnitzky, W. J. Schneider, P. Stein
- MedicineCirculation
- 1 April 1995
Values of RR variability previously reported to predict death in patients with known chronic coronary heart disease are rarely found in healthy middle-aged individuals and should be rare when measures ofRR variability are used to screen groups of middle- aged persons to identify individuals who have substantial risk of coronary deaths or arrhythmic events.
Insights from the study of heart rate variability.
- P. Stein, R. Kleiger
- Medicine, BiologyAnnual Review of Medicine
- 1999
HRV in combination with other risk stratifiers, e.g. ejection fraction, can identify cardiac patients at especially high risk of mortality and many but not all interventions associated with increased HRV are also associated with better survival rates.
Time domain measurements of heart rate variability.
- R. Kleiger, P. Stein, M. Bosner, J. Rottman
- MedicineCardiology Clinics
- 1 August 1992
Change in Heart Rate and Heart Rate Variability During Treatment for Depression in Patients With Coronary Heart Disease
- R. Carney, K. Freedland, P. Stein, J. Skala, P. Hoffman, A. Jaffe
- Psychology, MedicinePsychosomatic Medicine
- 1 September 2000
It is suggested that treating depression with CBT may reduce heart rate and increase short-term HRV, which may have a beneficial effect on a risk factor for mortality in depressed patients with coronary heart disease.
Association of depression with reduced heart rate variability in coronary artery disease.
- R. Carney, R. D. Saunders, K. Freedland, P. Stein, M. Rich, A. Jaffe
- Medicine, PsychologyAmerican Journal of Cardiology
- 1995
Depressed patients with angiographically documented CAD have decreased HR variability, which may help explain the increased risk for cardiac mortality and morbidity in depressed CAD patients.
Effect of exercise training on heart rate variability in healthy older adults.
- P. Stein, A. Ehsani, P. Domitrovich, R. Kleiger, J. Rottman
- Medicine, EducationAmerican Heart Journal
- 1 September 1999
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