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- Publications
- Influence
The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus
- Alex Van Moerkercke, P. Steensma, +13 authors A. Goossens
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 15 June 2015
Significance Terpenoids are the largest group of plant-specialized metabolites and include many valuable bioactive compounds, such as the blockbuster anticancer drugs vincristine and vinblastine,… Expand
The basic helix-loop-helix transcription factor BIS2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus.
- Alex Van Moerkercke, P. Steensma, +8 authors A. Goossens
- Biology, Medicine
- The Plant journal : for cell and molecular…
- 1 October 2016
Monoterpenoid indole alkaloids (MIAs) are produced as plant defence compounds. In the medicinal plant Catharanthus roseus, they comprise the anticancer compounds vinblastine and vincristine. The… Expand