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Systematic evaluation of muscle coenzyme Q10 content in children with mitochondrial respiratory chain enzyme deficiencies.
Coenzyme Q10 content, pathology evaluation, and electron transport chain (ETC) enzyme analysis were determined in muscle biopsy specimens of 82 children with suspected mitochondrial myopathy. DataExpand
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Bioequivalence of coenzyme Q10 from over-the-counter supplements
Abstract The objective of this study was to compare the relative bioavailability of two new products with solubilized and non-solubilized over-the-counter (OTC) coenzyme Q 10 products. Nine healthyExpand
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Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21.
Endogenous coenzyme Q10 is an essential cofactor in the mitochondrial respiratory chain, a potent antioxidant, and a potential biomarker for systemic oxidative status. Evidence of oxidative stressExpand
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Massive Venlafaxine Overdose Resulted in a False Positive Abbott AxSYM® Urine Immunoassay for Phencyclidine
Abstract Case report: A 13‐yr‐old girl overdosed on 48 × 150 mg venlafaxine (Effexor XR®). She was taking venlafaxine regularly for depression. Her only other medications included topical BenzamycinExpand
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Teaching pediatric laboratory medicine to pathology residents.
CONTEXT Laboratory data are essential to the medical care of fetuses, infants, children, and adolescents. However, the performance and interpretation of laboratory tests on specimens from theseExpand
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Clinical laboratory monitoring of coenzyme Q10 use in neurologic and muscular diseases.
Coenzyme Q10 (Q10) is available as an over-the-counter dietary supplement in the United States. While its use could be considered a form of alternative therapy, the medical profession has embracedExpand
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Validation and application of an HPLC-EC method for analysis of coenzyme Q10 in blood platelets.
Previous studies have indicated that analysis of coenzyme Q10 (CoQ10) in platelets may be clinically useful. The study objectives are to describe, validate and provide application of an HPLC-ECExpand
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CD8-positive B-cell chronic lymphocytic leukemia. A report of two cases.
Most B-cell chronic lymphocytic leukemias and a small normal subset of B lymphocytes express the T-cell-associated CD5 antigen; expression of other T-cell antigens has been reported only rarely. TheExpand
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Anticoagulant effects on plasma coenzyme Q(10) estimated by HPLC with coulometric detection.
BACKGROUND The proportion of reduced coenzyme Q(10) (Q(10)H(2)) in total coenzyme Q(10) (TQ(10)), referred to as the Q(10)H(2):TQ(10) ratio, may be used as a possible marker of in vivo oxidativeExpand
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Helicobacter pylori eradication in dyspeptic primary care patients: a randomized controlled trial of a pharmacy intervention.
OBJECTIVE To determine the effectiveness of structured adherence counseling by pharmacists on the eradication of Helicobacter pylori when using a standard drug treatment regimen. DESIGN RandomizedExpand
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