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Construction of integrated genetic linkage maps by means of a new computer package: JOINMAP.
- P. Stam
- 1 May 1993
The procedure performs a sequential build-up of the map and, at each step, a numerical search for the best fitting order of markers, and weighted least squares is used for the estimation of map distances. Expand
High resolution of quantitative traits into multiple loci via interval mapping.
The core of the method is the completion of any missing genotypic (QTL and marker) observations, which is embedded in a general and simple expectation maximization (EM) algorithm to obtain maximum likelihood estimates of the model parameters. Expand
Linkage Disequilibrium Mapping of Yield and Yield Stability in Modern Spring Barley Cultivars
- A. Kraakman, R. Niks, P. van den Berg, P. Stam, F. V. van Eeuwijk
- Biology, Medicine
- 1 September 2004
The results indicate that association mapping approaches can be a viable alternative to classical QTL approaches based on crosses between inbred lines, especially for complex traits with costly measurements. Expand
RECORD: a novel method for ordering loci on a genetic linkage map
A new method, REcombination Counting and ORDering (RECORD) is presented for the ordering of loci on genetic linkage maps. The method minimizes the total number of recombination events. The search… Expand
Two high-density AFLP® linkage maps of Zea mays L.: analysis of distribution of AFLP markers
This study demonstrates the relative ease of generating high-density linkage maps using the AFLP technology and identifies a number of epi-alleles, showing allelic variation in the CpNpG methylation only in the maize chromosomes. Expand
Use of locus-specific AFLP markers to construct a high-density molecular map in barley
A skeletal map with a uniform distribution of markers can be extracted from the high-density map, and can be applied to detect and map loci underlying quantitative traits, but the application of this map is restricted to barley species. Expand
Identification of QTLs for partial resistance to leaf rust (Puccinia hordei) in barley
The map positions of these QTLs did not coincide with those of the race-specific resistance genes, suggesting that genes for partial resistance and genes for hypersensitive resistance represent entirely different gene families. Expand
Comparison and integration of four barley genetic maps.
This integrated map contains 898 markers, covers 1060 cM, and removes many large gaps present in the individual maps, and based on this integrated map, geneticists and breeders can choose their favourite markers in any region of interest of the barley genome. Expand
Two levels of interference in mouse meiotic recombination.
- Esther de Boer, P. Stam, A. Dietrich, A. Pastink, C. Heyting
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 20 June 2006
Differences between the distributions of MSH4/RPA foci and MLH1 foci along synaptonemal complexes might suggest that CO interference occurs in two successive steps. Expand
The distribution of the fraction of the genome identical by descent in finite random mating populations
- P. Stam
- 1 April 1980
The probability distribution of the heterogenic (non-identical by descent) fraction of the genome in a finite monoecious random mating population has been derived and an explicit expression is given for the expected number of ‘external junctions’ (sites that mark the end of a heterogenic segment) per unit map length in any generation. Expand