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Mouse closed head injury model induced by a weight-drop device
- M. Flierl, P. Stahel, Kathryn M. Beauchamp, S. Morgan, W. Smith, E. Shohami
- Biology, Medicine
- Nature Protocols
- 1 September 2009
Traumatic brain injury represents the leading cause of death in young individuals. Various animal models have been developed to mimic human closed head injury (CHI). Widely used models induce head… Expand
Management of bleeding following major trauma: an updated European guideline
IntroductionEvidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes.MethodsThe multidisciplinary… Expand
Closed head injury—an inflammatory disease?
Closed head injury (CHI) remains the leading cause of death and persisting neurological impairment in young individuals in industrialized nations. Research efforts in the past years have brought… Expand
Inflammatory response in acute traumatic brain injury: a double-edged sword
- M. Morganti-Kossmann, M. Rancan, P. Stahel, T. Kossmann
- Current opinion in critical care
- 1 April 2002
Inflammation is an important part of the pathophysiology of traumatic brain injury. Although the central nervous system differs from the other organs because of the almost complete isolation from the… Expand
Analysis of Efficacy and Failure in Proximal Humerus Fractures Treated With Locking Plates
Objective: The purpose of this study was to determine the efficacy of proximal humerus locking plates (PHLP) and to clarify predictors of loss of fixation. Design: Retrospective review of patients… Expand
ROLE OF CEREBRAL INFLAMMATION AFTER TRAUMATIC BRAIN INJURY: A REVISITED CONCEPT
ABSTRACT— Neuroinflammation occuring after traumatic brain injury (TBI) is a complex phenomenon comprising distinct cellular and molecular events involving the injured as well as the healthy cerebral… Expand
Management of bleeding following major trauma: a European guideline
IntroductionEvidence-based recommendations can be made with respect to many aspects of the acute management of the bleeding trauma patient, which when implemented may lead to improved patient… Expand
Pancreatic infection in severe pancreatitis: the role of fungus and multiresistant organisms.
HYPOTHESIS Recent controlled clinical studies suggest a positive effect of early antibiotic treatment on late morbidity and mortality in severe acute pancreatitis. However, widespread use of… Expand
Direct retroperitoneal pelvic packing versus pelvic angiography: A comparison of two management protocols for haemodynamically unstable pelvic fractures.
OBJECTIVE To evaluate the outcomes of haemodynamically unstable cases of pelvic ring injury treated with a protocol focused on either direct retroperitoneal pelvic packing or early pelvic angiography… Expand
Preperitoneal pelvic packing/external fixation with secondary angioembolization: optimal care for life-threatening hemorrhage from unstable pelvic fractures.
- C. Burlew, E. Moore, +4 authors P. Stahel
- Journal of the American College of Surgeons
- 1 April 2011
BACKGROUND Preperitoneal pelvic packing/external fixation (PPP/EF) for controlling life-threatening hemorrhage from pelvic fractures is used widely in Europe but has not been adopted in North… Expand