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The high affinity human interleukin-3 receptor is a heterodimeric protein consisting of an alpha and beta c subunit. The beta c subunit is responsible for receptor signal transduction. We have shown(More)
Although tyrosine kinases are clearly activated after ligand engagement of the human IL-3R in both hematopoietic and nonhematopoietic cytoplasmic environments, a role for phospholipid hydrolysis and(More)