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Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud.
TLDR
It is shown that RA signalling during pre-segmentation stages is necessary for anteroposterior patterning in the CNS and for fin induction to occur. Expand
Cryptic speciation in a model invertebrate chordate
TLDR
The application of independent species concepts to clarify the phylogeographic structure of the ascidian Ciona intestinalis, a powerful model system in chordate biology and for comparative genomic studies, raises interest in a new tunicate genome as a gateway to studies in speciation and ecological adaptation of chordates. Expand
Hox gene expression in teleost fins and the origin of vertebrate digits
TLDR
A scheme for the fin–limb transition in which the distal autopods (digits) are neomorphic structures produced by unequal proliferation of the posterior part of an ancestral appendix is suggested. Expand
Anteroposterior patterning is required within segments for somite boundary formation in developing zebrafish.
TLDR
Observations indicate that a key consequence of the anteroposterior regionalisation of segments may be the induction of Eph and ephrin expression at segment interfaces and that Eph/ephrin signalling subsequently contributes to the formation of somite boundaries. Expand
Evolution of the nitric oxide synthase family in metazoans.
TLDR
Overall, NOS family evolution was the result of multiple gene and genome duplication events together with changes in protein architecture, resulting in three isoforms--I, II, and III--in current mammals. Expand
Concordant mitochondrial and nuclear DNA phylogenies for populations of the teleost fish Fundulus heteroclitus.
TLDR
Molecular phylogenies using mitochondrial DNA and nuclear alleles of the lactate dehydrogenase B locus were found to be concordant for populations of Fundulus heteroclitus ranging from Canada to Florida, with a clear separation between the northern and southern individuals. Expand
Mitogenomics reveals two cryptic species in Ciona intestinalis.
TLDR
Comprehensive comparative analysis of the mitochondrial genome of the two cryptic species revealed significant differences in gene order, size and number of noncoding regions, compositional features and divergence of protein-coding genes. Expand
Zebrafish Hoxa and Evx-2 genes: cloning, developmental expression and implications for the functional evolution of posterior Hox genes
TLDR
The structural organization and expression of Abd-B related zebrafish HoxA cluster genes as well as of Evx-2, a gene closely linked to the HoxD complex are analysed, showing that the genomic organization of Hoxa genes in fish resembles that of tetrapods albeit intergenic distances are shorter. Expand
Differential regulation of the zebrafish orthopedia1 gene during fate determination of diencephalic neurons
TLDR
The evolutionary importance of otp1 transcription factor in cell states of the diencephalon anlage and early neuronal progenitors is pinpointed and data indicate that morphogenetic mechanisms differentially regulate Otp1 expression in alar and basal plates. Expand
A molecular approach to the evolution of vertebrate paired appendages.
TLDR
Comparative molecular developmental biology is providing new insight into the similarities and differences in the morphologies of these homologous structures. Expand
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