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TLC Determination of Iodochlorhydroxyquin and Its Conjugate in Plasma
Abstract A simple, specific, reliable, and sensitive method for the determination of iodochlorhydroxyquin and/or its conjugate in biological fluids is described. The method is based on a quantitativeExpand
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Nitric Oxide‐Releasing Drugs
Abstract: Nitric oxide (NO) deficiency has been implicated in many pathologic processes, thus providing a solid biological basis for the use of NO replacement therapy. Exogenous NO sources constituteExpand
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Corrigendum to Pharmacological profile of a novel H2S-releasing aspirin [Free Radic. Biol. Med. 46/5 (2009) 586-592]
Corrigendum to “Pharmacological profile of a novel H2S-releasing aspirin” [Free Radic. Biol. Med. 46/5 (2009) 586–592] Anna Sparatore ⁎, Elena Perrino , Valerio Tazzari , Daniela Giustarini , RanieriExpand
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H2S releasing aspirin protects amyloid beta induced cell toxicity in BV-2 microglial cells
β-Amyloid (Aβ) plaques are characteristic hallmarks of Alzheimer's disease. In the present study, we examined the neuroprotective effects of S-aspirin, a hydrogen sulfide (H(2)S)-releasing aspirin,Expand
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Gastric Lesion-Preventing or -Potentiating Activity of Clonidine in Rats
The dual effects of clonidine on gastric experimental damage have been studied in the rat. At lower doses, clonidine prevents gastric lesions induced by oxotremorine plus neostigmine, probablyExpand
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ACS84, a novel hydrogen sulfide-releasing compound, protects against amyloid β-induced cell cytotoxicity
Hydrogen sulfide (H(2)S) is a novel neurotransmitter. We studied here the effect of ACS 84, a new H(2)S releasing compound, on the cytotoxicity induced by amyloid beta (Aβ) in microglia. TreatmentExpand
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Early and late phases in the formation by anti-inflammatory drugs of intestinal lesions in rats
It is well known that non-steroidal anti-inflammatory drugs (NSAIDs) cause gastrointestinal side-effects in both animals and humans. In recent years most attention has been devoted to the stomach,Expand
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Section Review: Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: Development of NSAIDs with reduced gastrointestinal and renal toxicity
While nonsteroidal anti-inflammatory drugs remain among the most widely used medications, their use continues to be associated with significant toxicity, particularly in the gastrointestinal tractExpand
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Role of intestinal microflora in maintaining indomethacin-induced intestinal lesions in rats
Indomethacin (IND) is known to cause gastrointestinal lesions when given in high doses to rats.
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