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The evolutionary dynamics of repetitive DNA in eukaryotes
Repetitive DNA sequences form a large portion of the genomes of eukaryotes. The 'selfish DNA' hypothesis proposes that they are maintained by their ability to replicate within the genome. TheExpand
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Saccharomyces cerevisiae and Saccharomyces paradoxus coexist in a natural woodland site in North America and display different levels of reproductive isolation from European conspecifics.
We report the isolation of multiple strains of Saccharomyces cerevisiae and Saccharomyces paradoxus from a natural woodland site in southeastern Pennsylvania, USA, using enrichment culturing in aExpand
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The evolution of mutation rates: separating causes from consequences
Natural selection can adjust the rate of mutation in a population by acting on allelic variation affecting processes of DNA replication and repair. Because mutation is the ultimate source of theExpand
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Evolution of high mutation rates in experimental populations of E. coli
Most mutations are likely to be deleterious, and so the spontaneous mutation rate is generally held at a very low value. Nonetheless, evolutionary theory predicts that high mutation rates can evolveExpand
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Allopatric Divergence, Secondary Contact, and Genetic Isolation in Wild Yeast Populations
In plants and animals, new biological species clearly have arisen as a byproduct of genetic divergence in allopatry. However, our understanding of the processes that generate new microbial speciesExpand
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Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae
BackgroundThe relationship between genetic variation in gene expression and phenotypic variation observable in nature is not well understood. Identifying how many phenotypes are associated withExpand
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Beneficial mutations and the dynamics of adaptation in asexual populations
We discuss the dynamics of adaptive evolution in asexual (clonal) populations. The classical ‘periodic selection’ model of clonal evolution assumed that beneficial mutations are very rare andExpand
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Saccharomyces paradoxus and Saccharomyces cerevisiae are associated with exudates of North American oaks.
Genetic hybridization and karyotypic analyses revealed the biological species Saccharomyces paradoxus and Saccharomyces cerevisiae in exudates from North American oaks for the first time. InExpand
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Evolution of competitive fitness in experimental populations of E. coli: What makes one genotype a better competitor than another?
An important problem in microbial ecology is to identify those phenotypic attributes that are responsible for competitive fitness in a particular environment. Thousands of papers have been publishedExpand
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Sympatric natural Saccharomyces cerevisiae and S. paradoxus populations have different thermal growth profiles.
Saccharomyces cerevisiae and its close congener S. paradoxus are typically indistinguishable by the phenotypic criteria of classical yeast taxonomy, but they are evolutionarily distinct as indicatedExpand
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