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A draft genome sequence of the pulse crop chickpea (Cicer arietinum L.).
Cicer arietinum L. (chickpea) is the third most important food legume crop. We have generated the draft sequence of a desi-type chickpea genome using next-generation sequencing platforms, bacterialExpand
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Detection of altered global DNA methylation in coronary artery disease patients.
Epigenetic modifications, especially alteration in DNA methylation, are increasingly being recognized as a key factor in the pathogenesis of complex disorders, including atherosclerosis. However,Expand
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Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine related genes for genetic and epigenetic studies
Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studiesExpand
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Homocysteine levels are associated with MTHFR A1298C polymorphism in Indian population
AbstractAn elevated level of homocysteine is an independent risk factor for cardiovascular diseases and is associated with other complex disorders. Homocysteine levels can be elevated due to dietaryExpand
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Partial purification and characterization of a highly thermostable and pH stable endoglucanase from a newly isolated Bacillus strain M-9
Cellulases to be employed for lignocellulose bioconversion for biofuel (ethanol) industry or for production of other specialty chemicals must be extremely robust to withstand harsh industrialExpand
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Effect of Processing on Chemical Composition and Antinutritional Factors in Chickpea Flour
Nutritional value of pulses is a widely accepted but the presence of antinutritional factors in its composition imposes a restriction in its consumption. Different processing treatments (germination,Expand
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Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients.
BACKGROUND The alteration in the epigenome forms an interface between the genotype and the environment. Epigenetic alteration is expected to make a significant contribution to the development ofExpand
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Surface ozone concentration and its behaviour with aerosols in the northwestern Himalaya, India
Abstract Surface ozone (O3), black carbon (BC) concentration and their relationship were established with PM10 and PM2.5 mass concentration at Mohal (31.9°N, 77.12°E, 1154 m amsl), a semi-urban site,Expand
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Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide.
Cytosine methylation in mammals is important for epigenetic control of the transcriptome. Although altered methylation is frequently encountered in disease situations, particularly cancer, theExpand
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Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription.
The factors and mechanisms underlying the differential activity and regulation of eukaryotic RNA polymerase II on different types of core promoters have remained elusive. Here we show that theExpand
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