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Exploiting the short wavelength gain of silica-based thulium-doped fiber amplifiers.
Short wavelength operation (1650-1800 nm) of silica-based thulium-doped fiber amplifiers (TDFAs) is investigated. We report the first demonstration of in-band diode-pumped silica-based TDFAs working… Expand
Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
- Stephen C Hughes, P. Shardlow, +4 authors Victoria M Rousell
- Chemistry, Medicine
- Drug Metabolism and Disposition
- 1 November 2008
The purpose of this study was to investigate the metabolism and disposition of fluticasone furoate, an enhanced-affinity glucocorticoid receptor agonist, in humans. In a two-part, open-label design… Expand
Silica-based thulium doped fiber amplifiers for wavelengths beyond the L-band
- Y. Jung, Z. Li, +9 authors D. Richardson
- Materials Science, Computer Science
- Optical Fiber Communications Conference and…
- 20 March 2016
We present a suite of silica-based thulium-doped fiber amplifiers (TDFAs) operating across the 1650-2050nm waveband. Expand
100 kW peak power picosecond thulium-doped fiber amplifier system seeded by a gain-switched diode laser at 2 μm.
We report on the generation of picosecond pulses at 2 μm directly from a gain-switched discrete-mode diode laser and their amplification in a multistage thulium-doped fiber amplifier chain. The… Expand
The disposition of gemifloxacin, a new fluoroquinolone antibiotic, in rats and dogs.
- J. Ramji, N. E. Austin, +7 authors P. Shardlow
- Chemistry, Medicine
- Drug metabolism and disposition: the biological…
- 1 April 2001
Gemifloxacin is a fluoroquinolone antibacterial compound with enhanced affinity for bacterial topoisomerase IV and is being developed for the treatment of respiratory and urinary tract infections.… Expand
High gain holmium-doped fibre amplifiers.
We investigate the operation of holmium-doped fibre amplifiers (HDFAs) in the 2.1 µm spectral region. For the first time we demonstrate a diode-pumped HDFA. This amplifier provides a peak gain of 25… Expand
First demonstration of a 2μm few-mode TDFA for mode division multiplexing.
We report the first demonstration of an inline few-mode thulium doped fiber amplifier (TDFA) operating at 2μm for mode division multiplexed transmission. Similar gain and noise figure performance for… Expand
Cladding shaping of optical fibre preforms via CO2 laser machining
Double-clad silica fibres used in high power lasers typically comprise a core doped with a laser active ion, a silica inner-cladding pump guide and a low refractive index outer polymer coating for… Expand
Optimising Tm-doped silica fibres for high lasing efficiency
Two-micron lasers are of great interest for a range of applications, from spectroscopy to polymer machining and laser surgery, as well as being an important stepping stone for wavelength generation… Expand
Metabolism and disposition of 14C-granisetron in rat, dog and man after intravenous and oral dosing.
- S. Clarke, N. E. Austin, +7 authors F. Woods
- Xenobiotica; the fate of foreign compounds in…
1. The disposition and metabolic fate of 14C-granisetron, a novel 5-HT3 antagonist, was studied in rat, dog, and male human volunteers after intravenous and oral administration. 2. Complete… Expand