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Antiemetic prophylaxis does not improve outcomes after outpatient surgery when compared to symptomatic treatment.
Although PonV is unpleasant, the data indicate little difference in outcomes when routine prophylactic medications are administered versus simply treating PONV should symptoms occur. Expand
Postoperative Nausea and Vomiting and Outcome
The concept of evidence-based medicine has gained considerable support over the past decade and is typical for evidence based recommendations to incorporate a grading scheme based on the perceived strength of the scientific evidence. Expand
Pharmacokinetics of Dopamine in Healthy Male Subjects
- D. Macgregor, T. Smith, R. Prielipp, J. Butterworth, R. James, P. Scuderi
- 1 February 2000
Despite a homogeneous population of healthy male subjects and weight-based dosing, there was 10- to 75-fold intersubject variability in plasma dopamine concentrations, making standard pharmacokinetic modeling of less utility than for other drugs. Expand
Multimodal Antiemetic Management Prevents Early Postoperative Vomiting After Outpatient Laparoscopy
It is concluded that both multimodal management and routine monotherapy antiemetic prophylaxis resulted in an increased level of patient satisfaction than symptomatic treatment in this high-risk population of women undergoing outpatient laparoscopy. Expand
Pharmacology of Antiemetics
- P. Scuderi
- International anesthesiology clinics
Improvement in the understanding of the physiologic mechanisms of nausea and vomiting as well as the introduction of new pharmacologic agents has led to a proliferation of clinical trials of antiemetic therapy over the past 10 years. Expand
Treatment of Postoperative Nausea and Vomiting after Outpatient Surgery with the 5‐HT3 Antagonist Ondansetron
Ondansetron, in doses less than 8 mg, is a safe, effective antiemetic for treating postoperative nausea and vomiting in patients following outpatient surgery. Expand
Substance P (Neurokinin-1) Antagonist Prevents Postoperative Vomiting after Abdominal Hysterectomy Procedures
Oral CP-122,721 200 mg decreased emetic episodes compared with ondansetron (4 mg intravenously) during the first 24 h after gynecologic surgery; however, there was no difference in patient satisfaction. Expand
Pulmonary hemorrhage associated with negative-pressure pulmonary edema.
Infected radial artery pseudoaneurysms occurring after percutaneous cannulation.
The duration of radial artery cannulation was significantly longer in patients who developed a pseudoaneurysm than in those patients who did not suffer this complication, and patients in whom infected RAPAs occurred tended to be older than the average age for all patients admitted to the intensive care unit (ICU). Expand
Postoperative sore throat: more answers than questions.
- P. Scuderi
- Anesthesia and analgesia
- 1 October 2010
In this issue of Anesthesia & Analgesia, 4 articles describe simple prophylactic measures that seem to significantly reduce the incidence of postoperative sore throat. Expand