• Publications
  • Influence
Antiinflammatory activity and bioavailability of percutaneous piroxicam.
Both the topical and the percutaneous antiinflammatory potencies of a topical formulation of piroxicam were investigated using as reference standards nonsteroid and steroid antiinflammatory drugsExpand
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Gastroprotective effects of morniflumate, an esterified anti-inflammatory drug.
An experimental study on morniflumate, the beta-morpholinoethyl ester of niflumic acid, was undertaken in the rat to test its gastroprotective and "cytoprotective" properties and to assess itsExpand
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Cardiovascular Effects of Nicardipine in Anesthetized Open-Chest Dogs in the Absence and Presence of β-Adrenergic Receptor Blockade: A Comparison with Nifedipine and Verapamil
Summary: Nicardipine, a new 1,4-dihydropyridine calcium-entry blocker, was assessed for cardiovascular effects against nifedipine and verapamil in anesthetized open-chest beagle dogs, in the absenceExpand
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A gastroprotective anti-inflammatory agent: theβ-morpholinoethyl ester of niflumic acid (morniflumate)
In several animal models orally administered morniflumate, the β-morpholinoethyl ester of niflumic acid, proved almost equal to the parent compound in anti-inflammatory, analgesic and antipyreticExpand
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β2‐Adrenoceptor blockade is the basis of guinea‐pig bronchial hyper‐responsiveness to leukotriene C4 and other agonists
1 Four β‐adrenoceptor antagonists, namely (−)‐propranolol, (+)‐propranolol, ICI‐118551 and (±)‐practolol, were investigated for their effects on leukotriene C4 (LTC4)‐induced bronchoconstriction inExpand
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Effects of iodinated contrast media on erythrocytes. I. Effects of canine erythrocytes on morphology.
A study was performed with the scanning electron microscope in order to describe the morphological changes induced in erythrocytes in vitro by a series of iodinated radiopaque compounds designed forExpand
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Piroxicam pharmacologic activity and gastrointestinal damage by oral and rectal route. Comparison with oral indometacin and phenylbutazone.
An experimental comparative study was conducted on 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide (piroxicam), indometacin and phenylbutazone for antiinflammatory andExpand
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Biliary excretion of contrast media.
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