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Antiinflammatory activity and bioavailability of percutaneous piroxicam.
Both the topical and the percutaneous antiinflammatory potencies of a topical formulation of piroxicam were investigated using as reference standards nonsteroid and steroid antiinflammatory drugs… Expand
Azabicycloalkyl benzimidazolones: Interaction with serotonergic 5-HT3 and 5-HT4 receptors and potential therapeutic implications
Gastroprotective effects of morniflumate, an esterified anti-inflammatory drug.
An experimental study on morniflumate, the beta-morpholinoethyl ester of niflumic acid, was undertaken in the rat to test its gastroprotective and "cytoprotective" properties and to assess its… Expand
Cardiovascular Effects of Nicardipine in Anesthetized Open-Chest Dogs in the Absence and Presence of β-Adrenergic Receptor Blockade: A Comparison with Nifedipine and Verapamil
- S. Bongrani, Roberta Razzetti, P. Schiantarelli
- Journal of cardiovascular pharmacology
- 1 September 1985
Summary: Nicardipine, a new 1,4-dihydropyridine calcium-entry blocker, was assessed for cardiovascular effects against nifedipine and verapamil in anesthetized open-chest beagle dogs, in the absence… Expand
A gastroprotective anti-inflammatory agent: theβ-morpholinoethyl ester of niflumic acid (morniflumate)
In several animal models orally administered morniflumate, the β-morpholinoethyl ester of niflumic acid, proved almost equal to the parent compound in anti-inflammatory, analgesic and antipyretic… Expand
β2‐Adrenoceptor blockade is the basis of guinea‐pig bronchial hyper‐responsiveness to leukotriene C4 and other agonists
- S. Bongrani, G. Folco, Roberta Razzetti, P. Schiantarelli
- Chemistry, Medicine
- British journal of pharmacology
- 1 August 1983
1 Four β‐adrenoceptor antagonists, namely (−)‐propranolol, (+)‐propranolol, ICI‐118551 and (±)‐practolol, were investigated for their effects on leukotriene C4 (LTC4)‐induced bronchoconstriction in… Expand
Effects of iodinated contrast media on erythrocytes. I. Effects of canine erythrocytes on morphology.
A study was performed with the scanning electron microscope in order to describe the morphological changes induced in erythrocytes in vitro by a series of iodinated radiopaque compounds designed for… Expand
Piroxicam pharmacologic activity and gastrointestinal damage by oral and rectal route. Comparison with oral indometacin and phenylbutazone.
An experimental comparative study was conducted on 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide (piroxicam), indometacin and phenylbutazone for antiinflammatory and… Expand
Potentiation of leukotriene C4 bronchoconstriction by beta-adrenoceptor antagonists in the guinea pig.