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Cellular retinol‐binding protein I is essential for vitamin A homeostasis
The gene encoding cellular retinol (ROL, vitA)‐binding protein type I (CRBPI) has been inactivated. Mutant mice fed a vitA‐enriched diet are healthy and fertile. They do not present any of theExpand
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Growth Arrest and Decrease of α-SMA and Type I Collagen Expression by Palmitic Acid in the Rat Hepatic Stellate Cell Line PAV-1
Liver fibrosis is characterized by an activation of hepatic stellate cells (HSC). During primary culture HSC evolve from a quiescent into an activated phenotype which is characterized by α-smoothExpand
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Concentrations of isoflavones in plasma and urine of post-menopausal women chronically ingesting high quantities of soy isoflavones.
Soy food or food supplements based on soy containing isoflavones (Isos) are increasingly available in Western countries. However, the variability of Isos levels in urine and plasma in humans duringExpand
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Influence of ethnic origin (Asian v. Caucasian) and background diet on the bioavailability of dietary isoflavones.
Soya isoflavones: genistein and daidzein are increasingly consumed in Western countries. Their beneficial effects are discussed considering nutrition and health in Asia. The present study aimed toExpand
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Analytical, Nutritional and Clinical Methods ELISA as a new method to measure genistein and daidzein in food and human fluids
Widely distributed in the plant kingdom, phytoestrogens, like soy isoflavones are found in plant protein extracts at varying levels depending on culture conditions and cultivars. Their increasinglyExpand
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Effect of vitamin A status at the end of term pregnancy on the saturation of retinol binding protein with retinol.
BACKGROUND Vitamin A (retinol), which is required for normal fetal development and successful gestation, circulates in the blood bound to a specific protein, the retinol binding protein (RBP). LittleExpand
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PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol.
During liver fibrogenesis or long term culture, hepatic stellate cells (HSCs) evolved from "quiescent" to activated phenotype called "myofibroblast-like", a transition prevented by retinoic acidExpand
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Bioavailability and urinary excretion of isoflavones in humans: effects of soy-based supplements formulation and equol production.
Soy isoflavones (IF) are of particular interest for their possible estrogenic effects on the symptoms of menopause. The bioavailability of IF is clearly a factor influencing their biologicalExpand
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Possible mechanisms of weight loss of Siberian hamsters (Phodopus sungorus sungorus) exposed to short photoperiod
Several weeks of short day photoperiod (SD) exposure promote a dramatic decrease of white adipose tissue (WAT) mass in Siberian hamsters(Phodopus sungorus sungorus). This slimming effect isExpand
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Treatment of the rat hepatic stellate cell line, PAV‐1, by retinol and palmitic acid leads to a convenient model to study retinoids metabolism
The main site of vitamin A storage in the liver is the hepatic stellate cells (HSC). Involvement of HSC in vitamin A metabolism has mainly been studied using primary culture, which represents theExpand
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