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Increased prediction accuracy using a genomic feature model including prior information on quantitative trait locus regions in purebred Danish Duroc pigs
BackgroundIn animal breeding, genetic variance for complex traits is often estimated using linear mixed models that incorporate information from single nucleotide polymorphism (SNP) markers using aExpand
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Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster
Predicting individual quantitative trait phenotypes from high-resolution genomic polymorphism data is important for personalized medicine in humans, plant and animal breeding, and adaptive evolution.Expand
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Life extension and the position of the hormetic zone depends on sex and genetic background in Drosophila melanogaster
Hormesis, the beneficial effect of a mild stress, has been proposed as a means to prolong the period of healthy ageing as it can increase the average lifespan of a cohort. However, if we want to useExpand
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Heat and cold-induced male sterility in Drosophila buzzatii: genetic variation among populations for the duration of sterility
Here we studied three phenotypic traits in Drosophila buzzatii that are strongly effected by temperature, and are expected to be closely associated with fitness in nature. The traits measured wereExpand
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Local adaptation of stress related traits in Drosophila buzzatii and Drosophila simulans in spite of high gene flow
We addressed the question if local adaptation to a thermal gradient is possible in spite of a high gene flow among closely spaced populations of two species of Drosophila from the island of La GomeraExpand
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Longevity for free? Increased reproduction with limited trade-offs in Drosophila melanogaster selected for increased life span
Selection for increased life span in Drosophila melanogaster has been shown to correlate with decreased early fecundity and increased fecundity later in life. This phenomenon has been ascribed to theExpand
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Temperature-Induced Hormesis in Drosophila
The phenomenon that a mild exposure to an otherwise detrimental stress factor can be beneficial, termed hormesis, is well known for many organisms and life-history traits (Khazaeli et al. 1997; LeExpand
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Developmental acclimation affects clinal variation in stress resistance traits in Drosophila buzzatii
Patterns of clinal genetic variation in Drosophila are often characterized after rearing at constant temperatures. However, clinal patterns might change after acclimation if populations differ inExpand
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Down regulation of Hsp70 expression level prolongs the duration of heat-induced male sterility in Drosophila buzzatii
Summary 1 The relationship between heat shock protein Hsp70 expression level and the duration of heat-induced male sterility was investigated in four populations of Drosophila buzzatiiExpand
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Flies selected for longevity retain a young gene expression profile
We investigated correlated responses in the transcriptomes of longevity-selected lines of Drosophila melanogaster to identify pathways that affect life span in metazoan systems. We evaluated the geneExpand
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