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Electrophysiological response to thyrotropin-releasing hormone of rat lactotrophs in primary culture.
The response of rat pituitary cells to thyrotropin-releasing hormone (TRH) in primary culture was studied in the whole-cell configuration with the patch-clamp technique. Prolactin (PRL)-containingExpand
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Regulation of intracellular chloride concentration in rat lactotrophs: possible role of mitochondria
Increasing evidence is accumulating for the involvement of chloride ions in the stimulus‐secretion coupling of pituitary cells. We show that the mean intracellular chloride concentration [Cl−]i ofExpand
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Long-term effects of calcium availability on prolactin and protein synthesis in human decidual cells.
Ever since decidual cells were recognized as the source of decidual prolactin (dPRL), very few reports have dealt with the role of calcium (Ca2+) on dPRL synthesis and release. In a recent work, weExpand
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Intracellular pH in individual pituitary cells: measurement with a dual emission pH indicator.
Intracellular pH (pHi) can now be measured at the single cell level using dual emission wavelength microspectrofluorimetry with the fluorescent pH indicator SNARF 1 and its membrane permeantExpand
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Effects of Cl– Substitution on Electrophysiological Properties, Ca2+ Influx and Prolactin Secretion of Rat Lactotropes in vitro
In this study, we compared the effects of different chloride (Cl<sup>–</sup>) substitutes – methane sulfonate (CH<sub>3</sub>SO<sup>–</sup><sub>3</sub>), bromide (Br<sup>–</sup>), nitrateExpand
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Calcium homeostasis in growth hormone (GH)-secreting adenoma cells: effect of GH-releasing factor.
Human GH-secreting tumors are heterogenous regarding their basal secretory activity and response to GH-releasing factor (GRF). We have investigated whether such different secretory properties couldExpand
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Regulation of intracellular pH in rat lactotrophs: involvement of anionic exchangers.
Regulation of the intracellular pH (pHi) of normal rat lactotrophs was studied. As this cell type, cultured with 10% FCS, can achieve a relatively alkaline pHi (7.3-7.5), we investigated the presenceExpand
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Local effect of the blastocyst on estrogen and progesterone receptors in the rat endometrium.
Nuclear receptors for both estradiol and progesterone were present in twofold higher concentrations in implantation sites than in nonimplantation regions of the endometrium of 6-day pregnant rats.Expand
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Tamoxifen reduces calcium currents in a clonal pituitary cell line.
The effect of the anti-estrogen Tamoxifen (Tx) on membrane electrical properties and the underlying calcium (Ca2+) conductances was examined in the clonal pituitary cell line GH3/B6 which exhibitsExpand
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Estrogen receptor development in the absence of growth hormone and prolactin: Studies in dwarf mice
The concentration of high-affinity estradiol binding sites in the uteri and pituitaries of normal and two dwarf strains of mice was studied. The two dwarf strains are characterized by their totalExpand
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