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A method for estimating the probability of adverse drug reactions
It was shown that the ADR probability scale has consensual, content, and concurrent validity and may be applicable to postmarketing drug surveillance.
An international perspective on Tourette syndrome: selected findings from 3500 individuals in 22 countries
- R. Freeman, D. Fast, L. Burd, J. Kerbeshian, M. Robertson, P. Sandor
- Psychology, MedicineDevelopmental medicine and child neurology
- 1 July 2000
A multisite, international database of 3500 individuals diagnosed with Tourette syndrome, with wide variation among sites, can be used as the entry point for further research when large samples are studied and generalizability of results is important.
Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome.
It is confirmed that psychiatric comorbidities are common among individuals with TS, demonstrates that most comor bidities begin early in life, and indicates that certain comorbiities may be mediated by the presence of comorbrid OCD or ADHD.
Analysis of shared heritability in common disorders of the brain
It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
The Tourette Syndrome Diagnostic Confidence Index
The DCI is a useful, practicable instrument in the clinic or research practice allowing an assessment of lifetime likelihood of TS and its correlation with other instruments and associations with psychopathology provide support for its being a lifetime measure of TS.
Canadian Guidelines for the Evidence-Based Treatment of Tic Disorders: Pharmacotherapy
- T. Pringsheim, A. Doja, P. Sandor
- Medicine, PsychologyCanadian journal of psychiatry. Revue canadienne…
- 1 March 2012
A systematic review of the literature on the treatment of tic disorders in children and adults found that when tics are more distressing and interfering, the need for tic suppression to improve quality of life is stronger, and patients and clinicians may be more willing to accept the risks of pharmacotherapy.
Aggressive Behaviour in Children with Tourette Syndrome and Comorbid Attention-Deficit Hyperactivity Disorder and Obsessive—Compulsive Disorder
- R. J. Stephens, P. Sandor
- Psychology, MedicineCanadian journal of psychiatry. Revue canadienne…
- 1 December 1999
Findings provide additional evidence that aggressive behaviour observed in children with TS may be associated with comorbid ADHD or OCD, independent of tic severity or age.
Development of optimal treatment tactics for alcohol withdrawal. I. Assessment and effectiveness of supportive care.
- J. M. Shaw, G. Kolesar, E. Sellers, H. Kaplan, P. Sandor
- MedicineJournal of clinical psychopharmacology
- 1 November 1981
Three quarters of hospitalized patients, without serious medical complications, in alcohol withdrawal respond to intensive supportive care, however, pharmacotherapy is essential for nonresponders and patients with hallucinations.
Risperidone in the Treatment of Tourette Syndrome: A Double-Blind, Placebo-Controlled Trial
- Y. Dion, L. Annable, P. Sandor, G. Chouinard
- Psychology, MedicineJournal of clinical psychopharmacology
- 1 February 2002
Treatment with risperidone was accompanied by an improvement in global functioning in patients with average to above-average impairment at baseline as measured by the Global Assessment of Functioning scale, and hypokinesia and tremor increased in the ris peridone group, but the effect on tremor was largely confined to subjects with higher baseline tremor scores.
Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture
The results indicate that there is some genetic overlap between these two phenotypically-related neuropsychiatric disorders, but suggest that the two disorders have distinct genetic architectures.