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Drosophila melanogaster as a model for elucidating the pathogenicity of Francisella tularensis
Drosophila melanogaster is a widely used model organism for research on innate immunity and serves as an experimental model for infectious diseases. The aetiological agent of the zoonotic diseaseExpand
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Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification
Elongator complex is required for formation of the side chains at position 5 of modified nucleosides 5-carbamoylmethyluridine (ncm5U34), 5-methoxycarbonylmethyluridine (mcm5U34), andExpand
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Outbreaks of Tularemia in a Boreal Forest Region Depends on Mosquito Prevalence
Background. We aimed to evaluate the potential association of mosquito prevalence in a boreal forest area with transmission of the bacterial disease tularemia to humans, and model the annualExpand
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Directed Screen of Francisella novicida Virulence Determinants Using Drosophila melanogaster
ABSTRACT Francisella tularensis is a highly virulent, facultative intracellular human pathogen whose virulence mechanisms are not well understood. Occasional outbreaks of tularemia and the potentialExpand
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The shared genome is a pervasive constraint on the evolution of sex-biased gene expression.
Males and females share most of their genomes, and differences between the sexes can therefore not evolve through sequence divergence in protein coding genes. Sexual dimorphism is instead restrictedExpand
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Cycles of light and dark co-ordinate reversible colony differentiation in Listeria monocytogenes
Recently, several light receptors have been identified in non‐phototrophic bacteria, but their physiological roles still remain rather elusive. Here we show that colonies of the saprophytic bacteriumExpand
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Gut microbiome and innate immune response patterns in IgE‐associated eczema
Gut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling.
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Buffering of Segmental and Chromosomal Aneuploidies in Drosophila melanogaster
Chromosomal instability, which involves the deletion and duplication of chromosomes or chromosome parts, is a common feature of cancers, and deficiency screens are commonly used to detect genesExpand
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Epidemiology and Ecology of Tularemia in Sweden, 1984–2012
Geographic distribution of cases was correlated with the locations of lakes and rivers.
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Effects of climate change on tularaemia disease activity in Sweden
Tularaemia is a vector-borne infectious disease. A large majority of cases transmitted to humans by blood-feeding arthropods occur during the summer season and is linked to increased temperatures.Expand
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