A relationship between increased peritoneal leptin levels and infertility in endometriosis
- E. Barcz, Łukasz Milewski, J. Malejczyk
- Medicine, BiologyGynecological Endocrinology
- 1 January 2008
The results revealed that the levels of peritoneal-fluid leptin did not correlate with different stage of endometriosis, however, they correlated with body mass index, which may suggest that increased leptin levels in theperitoneal fluid may play a role in pathogenesis of infertility.
Increased levels of human neutrophil peptides 1, 2, and 3 in peritoneal fluid of patients with endometriosis: association with neutrophils, T cells and IL-8.
- Łukasz Milewski, P. Dziunycz, J. Malejczyk
- Medicine, BiologyJournal of Reproductive Immunology
- 1 September 2011
Synthesis and anticancer effects of conjugates of doxorubicin and unsaturated fatty acids (LNA and DHA)
- Magdalena Mielczarek-Puta, M. Struga, P. Roszkowski
- Chemistry, BiologyMedicinal Chemistry Research
- 25 September 2019
Among the all derivatives, the conjugates formed by the amide and ester linkages were found to be more promising compared with conjugate formed only by theAmide linkage, and show high cytotoxicity toward the tumor cell lines and moderate cytotoxic towards the normal cell line.
Fentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis
- Piotr F. J. Lipiński, P. Kosson, J. Sadlej
- Chemistry, BiologyMolecules
- 1 February 2019
Interestingly, it was possible to find nonlinear relationships between the binding affinity and the volume of the N-chain and/or anilide’s aromatic ring, which is consistent with the apolar character of interactions involved in ligand–receptor binding.
Elevated ghrelin levels in the peritoneal fluid of patients with endometriosis: associations with vascular endothelial growth factor (VEGF) and inflammatory cytokines.
- P. Dziunycz, Łukasz Milewski, J. Malejczyk
- MedicineFertility and Sterility
- 1 December 2009
Association of leptin with inflammatory cytokines and lymphocyte subpopulations in peritoneal fluid of patients with endometriosis.
- Łukasz Milewski, E. Barcz, J. Malejczyk
- Medicine, BiologyJournal of Reproductive Immunology
- 1 October 2008
Anticancer and antimicrobial effects of novel ciprofloxacin fatty acids conjugates.
- A. Chrzanowska, P. Roszkowski, Anna Bielenica, W. Olejarz, Karolina Stępień, M. Struga
- Biology, ChemistryEuropean journal of medicinal chemistry
- 2019
Formal synthesis of (-)-podophyllotoxin through the photocyclization of an axially chiral 3,4-bisbenzylidene succinate amide ester--a flow photochemistry approach.
- K. Lisiecki, K. Krawczyk, P. Roszkowski, J. Maurin, Z. Czarnocki
- ChemistryOrganic and biomolecular chemistry
- 14 January 2016
A strategy for the stereoselective synthesis of cyclolignans related to podophyllotoxin and its derivatives and the photocyclization of a chiral atropoisomeric 1,2-bisbenzylidenesuccinate amide ester is developed.
Metabolism of N-Acylated-Dopamine
- D. Zając, G. Spólnik, P. Roszkowski, W. Danikiewicz, Z. Czarnocki, M. Pokorski
- Biology, ChemistryPLoS ONE
- 22 January 2014
It is concluded that OLDA enters the metabolic pathway of dopamine through methylation of exogenously supplemented OLDA via catechol-O-methyltransferase (COMT) under in vitro, ex vivo, and in vivo conditions using rat brain tissue.
PTPN22/LYP 1858C>T gene polymorphism and susceptibility to endometriosis in a Polish population.
- R. Płoski, P. Dziunycz, J. Malejczyk
- Biology, MedicineJournal of Reproductive Immunology
- 2009
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