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Patients with Prior Fractures Have an Increased Risk of Future Fractures: A Summary of the Literature and Statistical Synthesis
Numerous studies have reported increased risks of hip, spine, and other fractures among people who had previous clinically diagnosed fractures, or who have radiographic evidence of vertebralExpand
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Pre-existing fractures and bone mass predict vertebral fracture incidence in women.
OBJECTIVE To determine the independent contributions of bone mass and existing fractures as predictors of the risk for new vertebral fractures. SUBJECTS Postmenopausal Japanese-American women. Expand
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Intermittent cyclical etidronate treatment of postmenopausal osteoporosis.
Abstract Background. To determine the effects of etidronate (a bisphosphonate that inhibits osteoclast-mediated bone resorption) in the treatment of postmenopausal osteoporosis, we conducted aExpand
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Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents.
Some, but not all, antiresorptive agents have been shown to reduce the risk of nonvertebral fractures. Agents that significantly reduced nonvertebral fracture risk also appear to produce larger meanExpand
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Osteoporosis. Frequency, consequences, and risk factors.
  • P. Ross
  • Medicine
  • Archives of internal medicine
  • 8 July 1996
More than half of all women and about one third of men will experience osteoporotic fractures during their lives. Although no symptoms occur prior to fracture, bone mineral density and other riskExpand
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Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group.
We report here the second 2-yr extension of a clinical trial among postmenopausal women; 235 women continued blinded treatment with 5 or 10 mg alendronate daily, and 115 women who had been treatedExpand
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Clinical consequences of vertebral fractures.
  • P. Ross
  • Medicine
  • The American journal of medicine
  • 18 August 1997
People with vertebral fractures have greater pain, disability, and healthcare utilization, on average, than those without fractures. Most studies of acute pain and disability have been limited toExpand
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Prevention of bone loss with alendronate in postmenopausal women under 60 years of age. Early Postmenopausal Intervention Cohort Study Group.
BACKGROUND Estrogen-replacement therapy prevents osteoporosis in postmenopausal women by inhibiting bone resorption, but the balance between its long-term risks and benefits remains unclear. WhetherExpand
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Rapid Bone Loss Is Associated with Increased Levels of Biochemical Markers
  • P. Ross, W. Knowlton
  • Medicine, Biology
  • Journal of bone and mineral research : the…
  • 1 February 1998
We examined associations of biochemical markers of bone turnover with rapid bone loss, as measured by changes in bone mineral density (BMD). To improve the precision of bone loss estimates, calcanealExpand
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Predicting vertebral fracture incidence from prevalent fractures and bone density among non-black, osteoporotic women
We evaluated the ability of bone density and vertebral fractures at baseline to predict vertebral fracture incidence in a cohort of postmenopausal women with osteoporosis. The study population wasExpand
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