High Resolution X-ray Crystallography Shows That Ascorbate Is a Cofactor for Myrosinase and Substitutes for the Function of the Catalytic Base*
- W. Burmeister, S. Cottaz, P. Rollin, A. Vasella, B. Henrissat
- Chemistry, BiologyJournal of Biological Chemistry
- 15 December 2000
Activation of the hydrolysis of the glucosyl enzyme intermediate is further evidenced by the observation that ascorbate enhances the rate of reactivation of the 2-fluoro-glycosyl enzyme, leading to the conclusion that asCorbic acid substitutes for the catalytic base in myrosinase.
The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo.
- Dario Brunelli, M. Tavecchio, M. D’Incalci
- BiologyBiochemical Pharmacology
- 15 April 2010
Glucosinolate structural diversity, identification, chemical synthesis and metabolism in plants.
- I. Blažević, S. Montaut, N. Agerbirk
- 23 November 2019
Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (kaiware daikon) and its redox properties.
- J. Barillari, R. Cervellati, M. Paolini, A. Tatibouët, P. Rollin, R. Iori
- Biology, MedicineJournal of Agricultural and Food Chemistry
- 24 November 2005
The assessed reducing capacity of GRH suggests that R. sativus sprouts might possess potential for health benefits, and is related to its radical scavenging activity.
An overview on neuroprotective effects of isothiocyanates for the treatment of neurodegenerative diseases.
- S. Giacoppo, M. Galuppo, E. Mazzon
- 1 October 2015
Isothiocyanates: An Overview of Their Antimicrobial Activity against Human Infections
- Letizia Romeo, R. Iori, P. Rollin, P. Bramanti, E. Mazzon
- 1 March 2018
The evaluation of the potential use of ITCs to replace or support the common antibiotics and their mechanism of action against human pathogens for which the current therapeutic solutions are deficient and therefore of prime importance for public health is evaluated.
The Isothiocyanate Isolated from Moringa oleifera Shows Potent Anti-Inflammatory Activity in the Treatment of Murine Subacute Parkinson's Disease.
- S. Giacoppo, T. S. Rajan, E. Mazzon
- BiologyRejuvenation Research
- 1 February 2017
Results in vivo showed a higher efficacy of moringin compared with GMG not only to modulate the inflammatory pathway but also oxidative stress and apoptotic pathways, which can be used in clinical practice as a useful drug for the treatment or prevention of PD.
Original Synthesis of Linear, Branched and Cyclic Oligoglycerol Standards
A variety of authentic standards of linear, branched and cyclic oligomers of glycerol, with well-defined structures and degrees of polymerisation from 2 to 5, have been efficiently synthesised.…
Comparison of bioactive phytochemical content and release of isothiocyanates in selected brassica sprouts.
- G. D. De Nicola, M. Bagatta, R. Iori
- Biology, MedicineFood Chemistry
- 1 November 2013
Enzymatic, Chemical, and Thermal Breakdown of 3H-Labeled Glucobrassicin, the Parent Indole Glucosinolate
- S. Chevolleau, N. Gasc, P. Rollin, J. Tulliez
- 17 November 1997
The enzymatic, chemical, and thermal breakdown pathways of glucobrassicin, the major indolylmethyl glucosinolate of cruciferous vegetables, have been studied using synthetic 3H-labeled glucobrassicin…