• Publications
  • Influence
Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study
TLDR
Use of CT scans in children to deliver cumulative doses of about 50 mGy might almost triple the risk of leukaemia and doses ofabout 60 m Gy might triple therisk of brain cancer. Expand
Brain tumor epidemiology: Consensus from the Brain Tumor Epidemiology Consortium
TLDR
In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address. Expand
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.
TLDR
The results suggest that common DNA repair variants may affect the risk of adult brain tumors, especially meningioma. Expand
Associations between Polymorphisms in DNA Repair Genes and Glioblastoma
TLDR
It is suggested that common variation in DNA repair genes may be associated with risk for glioblastoma multiforme. Expand
Detectable clonal mosaicism and its relationship to aging and cancer
TLDR
Large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases. Expand
Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption
TLDR
In a meta-analysis adjusted for age, sex, smoking, and eigenvectors of population variation, two loci achieved genome-wide significance: 7p21 (P = 2.4×10−19), near AHR, and 15q24 (P¬5.2× 10−14), between CYP 1A1 and CYP1A2. Expand
A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits.
TLDR
This work proposes a method that exhaustively explores subsets of studies for the presence of true association signals that are in either the same direction or possibly opposite directions, and presents two illustrative applications for pooled analysis of a case-control study of glioma. Expand
The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research.
TLDR
This ongoing study, which reflects the single most comprehensive body of information ever assembled on childhood and adolescent cancer survivors, provides a dynamic framework and resource to investigate current and future questions about childhood cancer survivors. Expand
Polymorphisms in Apoptosis and Cell Cycle Control Genes and Risk of Brain Tumors in Adults
TLDR
The results suggest that common variants in the CASP8, CCND1, CCNH, and MDM2 genes may influence brain tumor risk. Expand
RadRAT: a radiation risk assessment tool for lifetime cancer risk projection.
TLDR
An online radiation risk assessment tool (RadRAT) which can be used to estimate the lifetime risk of radiation-related cancer with uncertainty intervals following a user-specified exposure history and new risk models for seven additional cancer sites, using data from Japanese atomic bomb survivors are developed. Expand
...
1
2
3
4
5
...