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Effect of Lecithin and silymarin on D-galactosamine induced toxicity in isolated hepatocytes and rats
To investigate Lecithin for its hepatoprotective activity against D-galactosamine (D-GalN) induced toxicity in freshly isolated rat hepatocytes and animal models. Freshly isolated rat hepatocytesExpand
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An Overview of Fermenter and the Design Considerations to Enhance Its Productivity
The function of the fermenter or bioreactor is to provide a suitable environment in which an organism can efficiently produce a target product—the target product might be cell biomass, metabolite andExpand
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Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer
Abstract 2-Quinolone analogs are powerful inhibitors of farnesyl transferase, and are a novel class of anticancer drugs. The present study focused on continual efforts to elucidate the anticancerExpand
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Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives induce apoptosis in HepG2 cells through p53 mediated intrinsic pathway
Abstract A series of novel 1,3,4-oxadiazole derivatives (OSD, OCOD, ONOD, OPD, COD, PMOD, and PCOD) were synthesized and characterized. Their structures were confirmed on the basis of IR, NMR andExpand
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Screening of plant Macaranga peltata for its antioxidant, antimicrobial and cytotoxicity activity
The plant Macaranga peltata (Euphorbiaceae) leaves and stem bark was tested for its in vitro antioxidant, antimicrobial and cytotoxicity activity using different methods. In vitro anti oxidantExpand
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Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells.
BACKGROUND Silymarin, a hepatoprotective agent, has poor oral bioavailability. However, the current dosage form of the drug does not target the liver and inflammatory cells selectively. The aim ofExpand
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Hepatoprotective properties of Caesalpinia sappan Linn. heartwood on carbon tetrachloride induced toxicity.
Aim of the study was to investigate the methanol and aqueous extracts of heartwood of C. sappan for its hepatoprotective activity against CCl4 induced toxicity in freshly isolated rat hepatocytes andExpand
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Pharmacological Perspective of Glycyrrhiza glabra Linn.: a Mini-Review
Plants have been major source of medicine in all cultures from ancient times. In the traditional system, various indigenous plants are being used in the diagnosis, prevention and elimination of acuteExpand
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Optimization of Cultural Conditions for Protease Production by a Fungal Species
Studies were carried out on a paddy soil fungal isolate identified to be a strain of Aspergillus niger from Manipal. The parameters that largely impact enzyme production viz., fermentation time,Expand
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Effect of Lecithin on d-Galactosamine Induced Hepatotoxicity Through Mitochondrial Pathway Involving Bcl-2 and Bax
Twenty four Wistar strain albino rats were used for the investigations. Lecithin 50 and 100 mg/kg b wt was administered for 1 week by oral route. Liver damage was induced by intra peritonealExpand
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