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Inhibition of transcription factor NF-kappaB by sesquiterpene lactones: a proposed molecular mechanism of action.
- P. Rüngeler, V. Castro, T. Schmidt
- Chemistry, BiologyBioorganic & medicinal chemistry
- 1 November 1999
Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kappaB.
- B. Siedle, A. García-Piñeres, I. Merfort
- Chemistry, BiologyJournal of medicinal chemistry
- 19 October 2004
TLDR
Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets.
- P. Rüngeler, G. Lyss, V. Castro, G. Mora, H. Pahl, I. Merfort
- BiologyPlanta medica
- 1 October 1998
TLDR
Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kappaB.
- E. Koch, C. Klaas, I. Merfort
- Biology, ChemistryBiochemical pharmacology
- 15 September 2001
Study of sesquiterpene lactones from Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-kappa B as molecular target.
- V. Castro, P. Rüngeler, I. Merfort
- BiologyPhytochemistry
- 2000
Anti-inflammatory activities of hypocretenolides from Leontodon hispidus.
- C. Zidorn, V. Dirsch, H. Stuppner
- Biology, ChemistryPlanta medica
- 1 December 1999
TLDR
Germacranolides from Mikania guaco.
- P. Rüngeler, V. Brecht, G. Tamayo-Castillo, I. Merfort
- ChemistryPhytochemistry
- 1 March 2001